Author Archives: Mark Pegram

Vitamin D Recommendations by the Institute of Medicine are WRONG!

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When the Institute of Medicine for the amount of vitamin D for health was published in December of 2010, they were off by over a factor of ten. The vitamin D experts at the time wrote extensively about this, but no one found the error in the IOM’s calculations. I also wrote about it extensively in December that year and you can find links from my posts of the many comments. A news article published in November 2014 by News Medical has this lead-in for Canadian health: Increasing vitamin D intake could prevent 37,000 deaths annually and save taxpayers billions. The study at the IOM was paid for by the US and Canada.

If we extrapolate this number for the US, it is 370,000 deaths and tens of billions (about ten times the population of Canada) that an adequate intake of vitamin D would prevent. Savings would not be as great as in Canada because the insurance companies would keep the savings. That is of course until their sales cost went down and they would have to adjust pricing for medical insurance. In Canada, the medical cost are taken from their taxes and paid directly to medical providers. The cost per capita for medical care is already about half of what it is in the US. This is also true for the EU as well. If you include the cost of medical insurance as taxes, then our tax rates is exceptionally high. The Supreme Court has ruled that medical insurance is a tax as health insurance is required by the government. Are we really funding 18% of our economy off of the illness and fear of illness of the population?

The discoverer of the error is Paul Veugelers, PhD of the University of Alberta. He found by statistical methods that around 8000IU is necessary to keep 97.5 percent of the population at or above 20 ng/ml for 25(OH)D. This is based on the same data that was used by the IOM. The IOM stated at the time that only 600IU of vitamin D was needed to keep the population at 20 ng/ml. This recommendation was for a ten pound baby as well as a three hundred pound adult. So much for common sense. Here is a link to the Grassroots Health Newsletter on the matter. TAKE ACTION! Click the link on to the Grassroots Health Newsletter and follow the instructions in the middle of the page to sign the petition to have the IOM review their findings. Or just click here sign this petition. To sign, just put your name and email address and make any comments that you would like. Grassroots Health through their testing of thousands of people have found that it will actually take about 7000IU per day.

Also, it would be great if you would share this information with friends and social media to avoid this continuous health disaster.  Or better, contact  your local congressman and raise h*ll! – Pandemic Survivor

New Nutraceutical, Metadichol® – Breathtaking Results!

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“One good nutraceutical can wipe out the drugs.” Dr. Stephen De Felice

As a regular reader, you have seen several post of the new form of policosanol as a small droplet emulsion, brand name, Metadichol®. (Historic Breakthrough in Health – A Natural Alternative to Vitamin D) This natural substance appears to present a new model for how healing should occur in the body. As a natural substance formed on sun splashed portions of plants, it appears to act in the body very similar to vitamin D. This is a claim in the one of the many patents covering Metadichol®. As you know, you cannot patent a natural substance; however, the novelty is the small droplet that easily absorbs into the body and blood stream where it can become active in cells.

Some of the claims in the patent for healing are as follows: malaria, acne, eczema, ganglion, lipoma, MRSA, wound healing, fungal infections, psoriasis, hair growth, wrinkles, kidney disease, regulates glucose, insulin resistance, Diabetes type 2, Cholesterol, improved lipid profiles, hypertension, kidney disease, heart disease, reduced protein oxidation or oxidative stress, TNF a – significant immune system function, and increases serum vitamin C.

This product has only been on the market since the last part of 2014 in Southeast Asia. The reports coming from that area are amazing in the variety and healing of many diseases. The amazing thing has been no side effects. Of course, since it can be found of most foods, there should be no side effects. This appears to fall into the first rule of medicine, do no harm. When I was first approach by the discoverer, I thought – yeah, yeah another nut found a way to make money. Now after two months, I am truly amazed at the results from my own experience.

My own experience was first the amazement that the pain from my wife’s shingles went away in just a couple of days. It is interesting to note that her primary care physician had identified the rash as shingles along the C3-C4 dermatome. My wife has experienced shingles before that went on for over six months. After four weeks, there was still some redness and my wife went to see a dermatologist who is a friend of the family (I may have instigated this visit because of my prior communication with the dermatologist about Metadichol®). The dermatologist said that it was not shingles, primarily because it had gone away so fast and the apparent appearance of the remaining rash. She described it as a rash of unknown origin. I suspect this type of healing is unfamiliar to the dermatologist.

As for myself, I had a hemorrhoid that shrank overnight after an application of Metadichol®. Also, I treated a wound that I had received from cutting wood. It healed very quickly without a scab formation which I found extremely interesting. After about four weeks of using Metadichol®, there were red formations on my arm and leg. They appeared to be like large pimples or a formation of a colony of bacteria that looked similar to the appearance of MRSA that I had five years ago. After a few days of treatment with the Metadichol®, the redness disappeared. I now wonder if these areas were not colonies of pathogens trying to escape from the action of the Metadichol®. Also, the lipomas are shrinking on our 13 year old dog. We simply spray a couple of sprays on her food every day. We tried to treat a lick granuloma on the dog’s leg. This appeared to work well for a couple of weeks, but the dog started to lick again and the inflammation still exists. We have not tried to increase the dose for the dog. Also intermittent treatment may be an issue as well.

The mechanisms for how the substance works is not truly understood. Dr. Raghavan, the discoverer believes that there is some form of communication that appears to give intelligence to the action of Metadichol®. He has tried the formulation with synthetic components of policosanol and it does not work. He believes that it may be plant and microbial DNA that gets extracted along with the policosanol. It would be interesting if the Metadichol® is also renewing the health of our microbiome and homeostasis is reached in the body through this symbiotic relationship. The consideration of how it may possibly work because of DNA that comes over is daunting when considering the amounts of GMO foods that we are now consuming.

There are to be publications about Metadichol® that will appear over the next several months. This will include information on how our genome reacts and treatment of some very serious diseases. It will be interesting the response of the medical and research communities. – Pandemic Survivor

“Human subtlety will never devise an invention more beautiful, more simple, or more direct than does Nature— because in her inventions, nothing is lacking— and nothing is superfluous.” Leonardo da Vinci

A New Model for Wellness

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What will the Twenty First Century of health present? The old paradigm of treating symptoms in hopes that the body will ultimately repair itself has failed. Drugs for symptom relief with many side effects and poor nutrition has caused the increased in much chronic disease. Now, at least 18 percent of the US economy deals with medical care in the form of health insurance, pharmaceuticals, and many medical procedures. We now must revert to the ancient healing processes of environment and food if we want be well. Our food supply has been taken over by cost of supply and efficiency of delivery. Our environment has confined us in air conditioned buildings with less than quality air, exposure to unsettling electromagnetic fields, and no sunshine. Now, with the understanding of our symbiotic relationship to the microbiome, we must understand the importance of the DNA that we consume.

Only recently, in the late 1990s, has the microbiome been defined. The microbiome contains ten times more cells than the human body. If the human body contains a trillion cells then the microbiome contains over ten trillion cells and its associated DNA. That is approximately 23,000 genes of our DNA and 1,000,000+ genes in the microbiome. This DNA relationship is constantly changing through our food supplies and how our body and the microbiome relates. It has been found that the microbiome communicates directly with the central nervous system. In essence forming a sophisticated communication system that leads us down a path to wellness or disease. Of course, the health of our brains dictates the regulation of the hormonal system for DNA expression. This never ending cascade of hormones drives our emotions and how we feel. Feeling well is the ultimate goal.

Environmental toxins significantly affect this symbiotic relationship of the human body to the microbiome. We are constantly bombarded with manmade molecules that may not be healthy for the community that lives within us. As a result, inflammation occurs causing us to go down the road toward chronic disease. The environmental toxins may well include constant stress. Stress not only upsets our endocrine system, but most likely upsets the homeostasis of our microbiome as well. Environment and food that we eat must be controlled to have a healthy life. Yes, our body and the microbiome are very adaptive. This is the only reason that we have the health that we do.

Through trial and error in diets, it now appears that the diets similar to the paleo diet are the healthiest to us. Please note there were no manmade molecules in ancient times to assault our systems and the relationship to the microbiome. Also we were constantly exposed to the rhythms of nature. A proper diet and exposure to nature is necessary for health. When we were exposed to toxins in nature, then disease usually occurred. There are many examples of this over time whether lead in the water or organic toxins from plants that should not be consumed. Over thousands of years, we learned what consumption of plants and animals made us healthy and what made us ill. This has been lost through specialization in science. Science, which studies only one thing at the time through control trials without consideration for the multiple variant environment in which we live. It is the correct combination of environment and consumption that we feel well.

I spent the Saturday afternoon, January 10, at a seminar by a local retired pediatrician, Dr. Bose Ravenel, Coauthor of The Diseasing of America’s Children. He has now come over to the understanding of functional medicine after forty three years of practice. When he first started to study functional medicine, he thought that the science would be weak. To his amazement, he discovered that the science was extensive. He has become amazed that nutrition is not taught as the number one understanding of doctors. It is only through wisdom with age has he come to this conclusion. The criticism that functional medicine is pseudoscience has been put to rest his mind after reading the literature for five years. With the start of practicing the use of food and environment for his own well being, his eyes have been opened.

What is going to be necessary to change this failed model of wellness and disease that we currently embrace? Our government has so embraced this paradigm for security of our economy that it may take many decades to overcome. That is of course if our economy does not collapse for other reasons. It may take a catastrophe that we don’t want to experience to regain a true understanding of health. It is truly immoral to support the largest sector of the economy off the illness of the nation as a means of production. It is my hope that leaders will arise to point us to a meaningful healthy understanding. However, it is only with individuals like you that are willing to read and research that we will ultimately change the current destructive model of health. That is through you feeling better and telling others about it. Thank You for taking the time to read. Go, tell others! – Pandemic Survivor

Synthetic Vitamin E Lung Congestion

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Do you supplement with a vitamin E or a multiple vitamin that has vitamin E in it. There is a good possibility that the vitamin E is artificial. That happened to me last winter. I kept having issues with some minor lung congestion and could not figure out what was causing it. Then Dr. Mercola wrote an article about artificial vitamin E and its relationship to lung cancer. The article described the difference between natural vitamin E and the artificial form in the supplement. Here is the article: Not Any Old Vitamin E Prevents, Reverses Lung Cancer. It was not that I was on the verge of lung cancer (or at least I hope not) but it was just lung congestion.

After reading the article, I disposed of the multiple vitamins that had vitamin E in it as DL-a-tocopherol acetate. From the article I discovered that this synthetic form of vitamin E is a by-product of the petrochemical industry and has significant endocrine- disruptive characteristics. Because of this disruptive characteristic it has been linked to prostate cancer as well as hemorrhagic stroke and pneumonia.

Are you blaming your present lung congestion on your environment from cold weather or even your belief that your house has mold or your HVAC has an issue. The first thing to do is to check your vitamins to see if you are getting the synthetic form of vitamin E. Natural vitamin E is always the d form like d-alpha(beta, etc)-tocopherol. If you see dl or DL, then toss it in the trash. The direction of chiral or rotation of this organic molecule makes a huge difference to your biology.  If you are still having lung congestion, look for other causes like artificial forms of beta-carotene and then other environmental causes.

What happened last winter after I threw the synthetic form of vitamin E into the trash? My lung congestion that had been going on for months went away in just a few days. – Pandemic Survivor

Historic Breakthrough in Health – Nano Policosanol

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“In questions of science, the authority of a thousand is not worth the humble reasoning of a single individual.” – Galileo Galilei

Nature will typically provide at least two pathways or redundancy for anything that is critical to the survival of life. Consider that we have two arms, two kidneys, two eyes, two lungs, etc. If you want to get more technical consider there are two substances to allow homocysteine to go to methionine [trimethylglycine (TMG or Betaine) or the combination of folate with vitamin B12] for the methylation cycle for the expression of genes. The discovery is a substance that works along some of the pathways of vitamin D and enhances the action of nutrients and more.

The remarkable thing about the action of this form of policosanol, as described in the patent, is that it does not drive up serum calcium. This has always been the issue with simply giving the hormone form of vitamin D to patients. Imagine anything that can work on physiological systems of the body without side effects. This natural substance has been consumed forever. Could this be the gift for an extremely healthy life? Like vitamin D in animals, it is also produced by the sun on plants and in many of our foods. The issue has been the ability of the body to absorb it so that it can get to where it needs to be active.   The new discovery is the effectiveness of a small droplet sized emulsion of policosanol. Policosanol is found as a waxy aliphatic alcohol on the leaves of sugar cane and in the husk of many grains and in other plants as well.   This may be reason that diets like the unprocessed paleo diet are so effective.

In conversations with Dr. P.R. Raghavan, he describes the finding as nature’s way of providing a pathway to health for animals who cannot obtain their vitamin D from the sun. He states that his discovery came from observing rats. The first thing that rats do is to eat grass when experiencing long periods without any exposure to sun. Grass makes the waxy alcohol on its leaves. “Rice-field Rats primarily reside in cultivated areas such as rice paddies and grasslands. It [where they reside] is largely dependent on human rice fields and plantations. Rice field rats shelter in burrows in soil, under rocks, and in logs”. It now makes me wonder when I see a dog eat grass if they are trying to achieve health from policosanol. Animals will do whatever is necessary for survival. Dr. Raghavan has been vigorous in making this understanding.

Consider the elephant with its hard dermal layer. How does it get its vitamin D? Or is its health from eating the policosanol in all the plants that it consumes.   “Asian elephants eat a wide variety of plants including grasses, shrubs, bamboo etc. While more than 100 different species may be eaten, only about 10 to 25 foods are likely to make up more than 8% of the diet. The percentage of grasses versus browse eaten varies seasonally; the nutrient value of grass is greatest early in the wet season, while that of leafy browse is higher in the dry season. Elephants do show choice in feeding: foods eaten do not necessarily match foods available. Crops such as bananas, sugar cane and paddy (rice) are favoured.” The sugar cane and paddy rice are very high in policosanol. The serum concentration of 25(OH)D for elephants is low compared to what is considered healthy for animals at an average of 16 ng/ml.

From Dr. Raghavan’s Into to Metadichol: “In the late 1880’s Dutch physician, Christiaan Eijkman was sent to the East Indies(now Indonesia to investigate why beriberi was so widespread in the region. Eijkman observed that hens in his Jakarta laboratory suffered symptons of nerve disease (polyneuritis) that were strikingly similar to those for beriberi – including muscle weakness, nerve degeneration, and paralysis. He then began a series of experiments to try to find a culprit organism, which he assumed was the cause.

He showed that the hens contracted the beriberi like polyneuritis soon after their feed was changed to polished rice – that is, rice whose outer husk had been removed. He also proved that by adding rice bran (the parts removed in polishing) to the hens’ food, the disease could be cured. The outer Husk contains Metadichol (policosanol).” We should clarify here that beriberi is commonly thought to be caused by vitamin B1 (Thiamine) deficiency, but Dr. Raghavan believes that the lack of policosanol was also a cause.

Emulsions are liquid colloids of droplets that are typically less than one micron in size. If you think about homogenized milk, it has fat droplets that range from 300nm to 500nm (0.3 microns to 0.5 microns). There are many small sized droplet emulsions that we normally use. Think about sugar in water, soap in water, or a supplement like vitamin E, vitamin A, vitamin D, vitamin K, etc. in water. The droplet size of the patented emulsion of policosanol, Metadichol®, is about 50nm in size.   This allows for easy absorption through the gut wall or through dermal layers if used topically.

Think about the many pathways that are described by Anthony W. Norman for health in his paper:
The History of the Discovery of Vitamin D and Its Daughter Steroid Hormone
Norman A.W. Ann Nutr Metab 2012;61:199–206 (DOI:10.1159/000343104)
It is truly astonishing the possibilities for health through vitamin D pathways of the vitamin D receptor. Consider this diagram derived from this paper for immune response:

Story02

Let’s take mast cells as an example in an autoimmune response. The mast cells become over active causing significant inflammation. The Metadichol®, name given in the patent, binds to the mast cell VDR and calms it down. As a result, the inflammation that is being caused disappears. Dr. Raghavan says, “Based on our invitro and invivo data Metadichol ® behaves as an agonist for one receptor and an antagonist or neutral antagonist or inverse agonist for another receptor.” The many cells that are involved in an immune reaction and other physiologies with the VDR makes the possibilities for health unlimited.

Dr. Raghavan likes to describe the VDR super family of nuclear receptors and the action of Metadichol® as follows: “A simplified way of looking at it is that the Vitamin D receptor (VDR) present in chromosome 12 in each and every cell is the conductor of an orchestra and he/she, is not relaying to the orchestra the proper cues. This will impact the performance of other members of the orchestra. Metadichol by acting on VDR restores the conductor to peak performance and ensures that both the conductor and the orchestra will perform at their peak potential (read; disease free).”

We have been scared from the sun for the last fifty years. It is time to take advantage of the nature’s gift from the sun, vitamin D in animals and policosanol in plants. This is truly a wonderful and historic discovery in nutritional health. I believe that it is a discovery worthy of the Nobel Prize! – Pandemic Survivor

Knowledge advances not by repeating known facts, but by refuting false dogmas. – Isaac Newton

Brief Bio: Dr P. R. Raghavan CEO of Nanorx Inc. has a Ph.D. in Organic Chemistry from Oregon State University, USA (1979) and a M.S in Chemistry (1972) from I.I.T Mumbai, India. . He has worked on drug discovery for over 25 years at Columbia University, Max-Planck Institute, Germany, Ciba-Geigy (now Novartis) and Boehringer-Ingelheim Pharmaceuticals. His fields of specialization are CNS, Inflammation, AIDS and ACE inhibitors. His experience in drug research includes Chiral synthesis, process, scale up and clinical research. He has been working for the last 12 years in the area of nutraceuticals and developing environmentally cost effective solutions for Bio-Diesel production.

Dr. Raghavan’s Business Philosophy: “Value for Money and Value for Many”

The Sun, Infectious Disease, or What Happens in the Dark

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Gen: 1:2 NIV, “Now the earth was formless and empty, darkness was over the surface of the deep…”

We have been scared out of the sun for the last fifty years. It has been constantly screamed at us about the danger of sun exposure. We have slathered huge amounts of sunscreen on our bodies when we do go into the sun. Also, with the invention of TV and computers, we have spent significantly more time inside than out during the recent decades. This has presented the question, “Have we created an opportunity for a major pandemic because of the reduction of vitamin D from low sun exposure?”

I thought a unique way of determining the answer to this question is to look at past pandemics. I also decided to look at just bubonic plague outbreaks as this is well documented over the last fifteen hundred years. There have been three major outbreaks.

First Outbreak

The first outbreak of bubonic plague began in Europe, Constantinople, in approximately 542. There was a significant event just prior that cause the solar incidence to be significantly reduced. This event occurred in approximately 536. The reduced sun and resulting cold and crop failures went on for many years. Michael the Syrian, who wrote “the sun became dark and its darkness lasted for one and a half years… Each day it shone for about four hours and still this light was only a feeble shadow…the fruits did not ripen and the wine tasted like sour grapes.”

Robert A. Dull of the University of Texas believes that this reduce solar incidence occurred because of a volcanic eruption in El Salvador. The volcano is named Llopango and its caldera forms Lake Llopango that is 11 x 17 km near the city of San Salvador. There is enough scientific evidence that Dull is certain the ash cloud from this eruption was the cause.

It is interesting to note that the disease was carried by rats, a nocturnal animal. It is easy to understand that nocturnal animals would have a much lower opportunity to receive vitamin D from any source. It is estimated that the plague killed approximately 50 million people in the Roman Empire alone.

Second Outbreak – The Black Death

This outbreak was believed to have begun in Mongolia in the earlier 1330’s. It then spread to Europe as merchant ships arrived from the Crimea in approximately 1347. It is reported that approximately a third of the population was killed in Europe. In looking for volcanic activity, I found that Mount Tarawera (New Zealand) erupted around AD 1315. The ash thrown from this event may have dropped temperatures around the globe and precipitated the Great Famine of 1315–1317 in Europe. This was also the start of the Little Ice Age. Again, we find significant reduction in solar incidence. Also, I would imagine people started to wear more clothing because of the cold. It is interesting to note that the world’s population increased in areas other than Europe.

Third Outbreak

The third outbreak started again in Eastern Asia in approximately 1855. It was mostly localized. It then spread to the rest of China and India in the 1890’s where approximately 12 million people died. I found volcanic activity from another major eruption of Mount Tarawera in 1886 and Krakatoa in 1883(Sunda Arc). Again the eruptions occurred just a few years before a major outbreak.

Are we a population of sun deficient, vitamin D deficient people waiting for another major pandemic to occur? This is a very unnerving scenario. We can only hope that the current outbreak of Ebola is localized to West Africa. Ebola is a disease that is believed to have originated with bats, a nocturnal animal. Have we discovered enough science to arrest the disease? With this concern, the incidence of sun cancer should be the least of your worries. Responsibly spend time in the sun. Don’t let your skin burn, but stay long enough to build your vitamin D3 stores. If you live in northern latitudes or stay inside, then supplement. It is not as good as the sun, but better than no vitamin D3. – Pandemic Survivor

NOAA “A New Look at the 1918/1919 El Nino Suggest Link to Flu Pandemic”
Earth Magazine   AAG: Eruption of El Salvador’s Llpango Explains A.D. 536 Cooling
Wiki Timeline of Volcanic Eruptions
Wiki Mount Tarawera (New Zealand)

The Microbiome – A New Model for Health

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sunday musting 2Buckminster Fuller: “You never change things by fighting the existing reality. To change something, build a new model that makes the existing model obsolete.”

What would a new model in medicine look like? Perhaps that new model has already been developed, but we have not begun to understand it. In the late 1990’s, a new paradigm in health was published. That is we live in a symbiotic relationship with a community of microbes. There are ten times more cells in this community of microbes than human cells within the body. There is also significantly more DNA in this community than human DNA that was discovered when trying to map the genome. Our model of genes or mutations of genes that affect our health is a poor model when we have ten times or more the genetics living with us that has to be properly expressed.

“You mean there is this tiny community of life living within our personal biosphere?” – Pandemic Survivor

“Yes, that is absolutely correct.” – A Cognizant Commentor “

“Hello, Mr. A. C. Commenter, where did you come from?” – PS

“It’s not commenter, it is Commentor. You introduced me a few weeks ago in a musing. You also got my name wrong in that post. A commenter is one that makes random suggestions where a commentor is one that typically has knowledge of a particular subject.” – ACC

“Sorry.” PS

“So there are ten times as many cells living in my body than my own human cells. That is certainly unnerving to think I have my own personal zoo living all over my body. Are they just in my gut?” –PS

“No they live everywhere in your body. There are literally trillions of these organisms that call your body home. A tiny bio home which lives everywhere in your body. Because this colony lives within you, it can either make you or break you. “ – ACC

“What do you mean by ‘make you or break you’?” -PS

“The way I like to think about our relationship with this colony is to imagine a bee keeper. The bee keeper goes about taking care of the hive to be sure there is plenty of fresh blossoms for them to collect the needs of the hive. Also the bee keeper makes sure that the colony always has a fresh place to store honey. The keeper may also take some of the honey for his own needs.  Certainly the bees also pollinate the fruits and vegetables in the keepers garden for an abundant yield.“  –ACC

“Wow! That is really interesting. I have never thought of anything like this. So I have to keep this living colony happy so that I am well? I always thought that anti bio substances were necessary to kept pathogens from causing disease. Every type of cleaner that I have purchased lately has some form of antibiotic in it. Even the dish washing detergent I bought last week.” – PS

“It is unfortunate that we have used such a large volume of chemicals that has significant impact on our friends that live with us. This destruction of their colonies has caused us much harm. If you think of it like the bee keeper analogy, so goes the colony, so goes the good fortune of the bee keeper. “ –ACC

“Interesting, a healthy hive, a healthy life or living symbiotically.” -PC

“Yes, that is exactly right. If you go out and kick over the hive, you will create an angry swarm of bees that attack you to protect their home. If you give them a place to live, and some nectar to keep them calm, they will re-track their anger. This may account for infectious disease as well as autoimmune diseases and allergies. It may also account for biochemical missteps as well. You introduce a pathogen (or a cougar in the hen house) that angers the hive or a substance that angers the hive and the attack of inflammation begins. You give them their natural needs and the hive calms down and stops attacking you. Pharmaceuticals under our existing paradigm of working on just human cells may actually anger the hive and cause severe inflammation commonly called side effects.” -ACC

“So ole Hippocrates was right two millennia ago. Medicine really is about food and keeping the ‘hive’ happy.” – PS

“Our present model of health has given us many great things for emergency healing, but I believe all the other diseases and possibly severe infections may be treated by keeping the microbiome well. I suspect this is the reason that chronic disease has not gotten any better since the understanding of DNA and the Central Dogma of molecular biology. We have totally ignored the environmental effect on expression of DNA and the DNA of our microbiome. The central dogma of saying that a gene or a gene mutation is the reason for disease is just wrong. It is like saying that you can throw a set of blueprints on a vacant lot and expect a building to spring up. It is the acts of the contractors and the skill of the crews that give you the building. The better you treat the workers, the better the building is likely to be.” – ACC

“That certainly is a new model of health. They actually named our present model central dogma? What arrogance! How can I learn more?” –PS

“Just read.” –ACC

Wiki – Microbiome

Central Dogma

National Institute of Health – Microbiome

The Miracle of the Sun

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You are a child again and it is the night before that long awaited event. It’s the evening before the little league play off game. You dream of that power shot you plan to hit over the right field fence. Perhaps it is the evening before your birthday or Christmas eve. You know that the doll you have been longing for is wrapped and waiting. In bed, you toss and turn in excitement and anticipation. You know what is about to happen is going to be so joyful and loving to you and everyone you know. I did not think this type of excitement can happen to an old man. It has happened to me in the last several weeks.

It is interesting to think of the things that are required for life. A life with abundant good health that is happy and joyful. What are those things that you need ? Without air, you would die in a few minutes. Without water, you would die in a few days. Without food maybe you could make it for a couple of weeks. How long would you make it without the sun? Without the sun you would have no food and possibly not enough heat to survive. And could you survive without love? Think of the trial in the 1930’s when they tried to feed babies without touching them. The trial was ended because the babies started to die. Yes air, water, food, sun, and love are needed for an abundant life.

For at least the last fifty years, our medical professionals have been scaring us from the sun. We have even told people, after Dr. Cook’s proclaimation that vitamin D would cause birth defects in the 1960’s, to limit any source of vitamin D. (Note: Dr. Cook was friends of the Kennedys and had great political and public attention.) Chronic disease has flourished in America as we have limited our exposure to sun. Now research on vitamin D has shown at least fifty health issues that have been proven by clinical trials to be caused by deficiency in this sun driven vitamin. Is that why all the people that I know over ninety enjoy spending time in the sun and make it a habit?

My excitement is over a second molecule that appears to work along the vitamin D pathways in the body. The two patents that I have been shown, each make ten unique medical claims that are beyond what we would expect of vitamin D. And yet this natural substance is completely safe as it has been consumed for years. The unique novelty of the formulation is in a form that allows the policosanol to enter the cell where our biological life happens. Yes that’s right, just policosanol, an extract primarily of the sun splashed portions of sugar cane and other sun washed plants.

I picked one of the disease claims and decided compare how the unique formulation worked in a similar way as vitamin D. The claim in the patent is that the formulation of policosonal is an inverse agonist for the vitamin D receptor.   Hunh? I had heard of agonist and antagonist, but not an inverse agonist. It is apparent to me, that this unique condition has not been defined in a way that a novice could understand. Here is an explanation at Wiki and at Pharmacology Corner

The Metadichol®, a name given the formulation in the patent, puts the vitamin D receptor in a state of action. It most likely is optimizing the performance of vitamin D to allow life. This is where the good stuff begins that causes you to really get excited. The sun created vitamin D has to go through several chemical/biological conversions to get to an active state that causes receptor action. This does not seem to be the case with Metadichol®. Once the policosanol is inside the cell, the receptors take action. Let’s take one of the claims to see if we can show the action of the sun over the years.

MRSA has become a true blight on mankind. The claim is that the Metadichol® healed MRSA. There are thousands of deaths in the US each year from this disease. Its sister, sepsis, claims hundreds of thousands of deaths each year. We know that vitamin D works well as an effective fighter of viruses, but to also treat bacterial infections is amazement. Of course this works in part through the production of a pathogen killer, cathelicidin antimicrobial peptide. The issue has always been, since Niels Finson was awarded the Nobel Prize in 1903 for healing lupus vulgaris with UV light, the side effect of toxicity. The effective treatment of using UV irradiation of serious infections has been phased out. Comments at the Vitamin D Council on sepsis and a history of treating infections with UV irradiation from The Guyer Institute. This history of treating infections is a very important read. Through the use of antibiotics, we have regressed over the last 110 years since the Niels Finson discovery of what nature has given us with the sun.

So what could happen at high levels of vitamin D from UV light without the toxicity – the action of vitamin D without having to worry about your serum calcium getting too high? What if you could keep your vitamin D really active without having to worry about toxicity? We suspect that it would be very effective in treating disease. It appears a unique symphony of action occurs when Metadichol® is introduced.  Here, the sun has provided us with two routes of health, vitamin D and a plant derivative, policosanol. A safe nutraceutical that has been consumed since ancient times. Who is this man that came up with a formulation to allow policosanol to be so effective? – Dr. P.R. Raghavan.

Brief Bio: Dr P. R. Raghavan CEO of Nanorx Inc. has a Ph.D. in Organic Chemistry from Oregon State University, USA (1979) and a M.S in Chemistry (1972) from I.I.T Mumbai, India. . He has worked on drug discovery for over 25 years at Columbia University, Max-Planck Institute, Germany, Ciba-Geigy (now Novartis) and Boehringer-Ingelheim Pharmaceuticals. His fields of specialization are CNS, Inflammation, AIDS and ACE inhibitors. His experience in drug research includes Chiral synthesis, process, scale up and clinical research. He has been working for the last 12 years in the area of Nutraceuticals and developing environmentally cost effective solutions for Bio-Diesel production.

As with all great leaps in science, it seems that one person has the vision and makes the jump in paradigm. It is never our huge institutions who make this leap. Institutions develop tunnel vision through the weighing down of institutional armor. Armor allows only a narrow view of life through a very small opening. In conversation with Dr. Raghavan, he believes that nature always gives us robustness and duplication in critical needs of life. For example, he states that we have two eyes, two kidneys, and two lungs. There are many examples in biology that have a second pathway, which depends on what our environment has given us. Dr. Raghavan states that his goal is to give the world a cost effective way to health for everyone.

Dr. Raghavan has licensed marketing companies in India, Asia, and soon the Middle East. This represents about sixty percent of the world’s population. He is presently looking for marketing companies for the rest of the world. His plan is to provide no one with an exclusive. Here is a link to the company licensed in Thailand, Polilex and a link to a store front page that is loaded with information.  

It is that evening before the big event. Life with a method of healing disease that is extraordinary. No longer do you have to cry at the loss of someone close because a serious disease has disrupted life. Only love, joy, and peace fill you. I am so excited – Pandemic Survivor.

A One Legged Man in a Butt Kicking Contest

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sunday musting 1I have always been amazed at this image. The idea of jumping and kicking at the same time is just more than my feeble brain can handle. If you are having trouble with the one legged man, think of a one legged stool. It would seem that in either case, doom is the imminent outcome.

Have you ever baked a cake or a pie? Think of a strawberry cake that is made only of strawberries. Not a cake or a pie, you have simply made a collection of strawberries. Or think of a strawberry cake that is made without sugar or fat or flour. It is like the sound of one hand clapping.

This is the problem when a specialist focuses on only “one thing.” The “one thing” has to participate in interactions from and to its environment. Imagine that you are all puckered to kiss and there is nothing opposite your lips, imaginary or otherwise. A handsome prince or a captivating princess, there to receive your pucker, is your desire. But is the kiss in the pucker of the lips only.  I am sure that a specialist in the pucker would think so. The FDA says that a pucker cannot be used to treat, heal, diagnose, or prevent any disease – not even a broken heart.  Of course the specialist would have to disclose any conflicts of interest like his association with the National Sphincter Association.

In the pathological and physiological processes of the human body, water, air, proteins, fat, carbohydrates, vitamins, and minerals would be “only the lonely” if they could not interact with each other. A body of water is a lake. A body of air is the sky. Birdie, birdie in the sky, I sure am glad that cows can’t fly. Oh, wait, wrong musing! This is the nature of our science and research when one specializes. There was a time when there was only one thing – “In the Beginning God…” The rest is just the dust of interactions. – A. Cognizant Commenter

Leading in Nutrients – The Affordable Care Act, Part II

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What are the natural or innate characteristics of leaders?   The significant characteristic of leadership is the ability to paint a picture of truth that others can understand. When the picture is false it becomes a lie.   The lie is where great leaders have failed us over the years. Much propaganda delivered in health and nutrition now makes it difficult for anyone to find the truth.   This includes you and your doctor.

The ability to paint a picture in leadership that others can understand is a great gift. It is not a developed gift but a gift or quality that is innate in the leader. Research was used to determine the qualities of a leader. Only one quality of leadership could be found through all ages of test participants. The participants were asked to drink a glass of water with lemon juice added – no sugar. They were then asked to describe how great the lemon water was to drink.   This was started with participants at the age of five. The children were then asked to go play. As they played, the researchers noticed that the children who were able to describe the lemon water as tasty without grimace, became the leaders in play. This test was repeated with groups through middle age with the same result.   Participants who were able to describe the lemon water as great to drink became “natural” leaders.

This gift of painting a picture that others can easily understand is what makes a leader great. There have been many examples of leadership when both the lie and the truth were used effectively. However, when the gift was used as a lie, eventually failure of the led was the result. Compare/contrast the words of leadership during WWII between Winston Churchill and Adolf Hitler.

Has this happened to us in health? The immediate example is the Affordable Care Act. A regular citizen, like yourself, has discovered some serious issues of lack of the truth. Richard Weinstein, MBA, Investment Advisor, found that Jonathan Gruber, the architect-advisor to the ACA, used less than truth to help the ACA pass legislation. Rich was frustrated for a year because he could not get the attention of the press. It was only after his findings became part of a legal challenge to the ACA that he found traction. Huffington Post Article: “This Philly-Based Investment Advisor Has Become Obamacare’s Digital Menace.” 11/11/2014

Rich was driven by the words that got the bill passed, “If you like your policy, you can keep your policy.” Last year, his health insurance policy was cancelled. The closest comparable policy was twice as much. He spent his nights researching the words of the architects of the ACA by reviewing videos that were available on the web. This past week, the Obama Administration was embarrassed by the videos and took immediate action. Obama declared that he wanted “Net Neutrality.” To me this sounds like double-speak as an effort to better control the internet. Glen Beck, on his morning radio show, called this declaration a “Trojan Horse” or subterfuge. A fear tactic was used this week with the words, “if you like Netflix, you can keep Netflix with net neutrality.”

Confusing and confounding findings are now included on a regular basis as a method to advance political advantages. Subterfuge is used in economics, in atmospheric science, and in evidence based medicine. The commonality is the complexity of finding truth. Findings by our elite scholars are being used to manipulate the people for the sole purpose of empire building.   Empire building is simply the maintenance and growth of any organization without concern for the stress on society as a whole.

We, as citizens with concern for the health of government and people, have to now take action. The internet is there for you to determine your own truth. However, be careful, the double-speak artists are paid well to paint beautiful pictures. We do need to follow the leadership of a plain citizen, Richard Weinstein. Have you had a health situation that could be healed with nutrients? It is up to you to talk about this with your friends and family and to help our ethical leaders understand what is happening to our society. – Pandemic Survivor