Hope for Psoriasis

Nanoscience has brought new hope for psoriasis. There have been many treatments available for psoriasis through the years. Now an over the county supplement has brought a solution. Metadichol is an over the counter supplement that is simply policosanol made into a small particle emulsion. Policosanol is the waxy substance found on the sun-splashed parts of plants. The case studies in this new paper that was just published are amazing in how it resolves the issues around this disease that has no apparent resolution in modern medicine.

Metadichol, A Novel ROR Gamma Inverse Agonist and Its Applications in Psoriasis

Raghavan PR* Nanorx Inc Chappaqua, New York, United states

Abstract

Psoriasis affects 3% of the population worldwide, and there is no known cure. Psoriasis is associated with an increased risk of psoriatic arthritis, lymphomas, cardiovascular disease, and Crohn’s disease. Psoriasis treatments today include steroid and vitamin D3 cream, ultraviolet light, and immune system suppressing medications such as methotrexate.

The T cells responsible for psoriasis are Th1 and Th l7 cells. IL-22, produced by Th17 cells, is crucial for the proliferation of keratinocytes. IL-22 with the help of IL-17 can induce the critical events of psoriasis. To maintain Th17 cells, IL-23 is required, and it is released from tumor necrosis factor-alpha (TNF-alpha) induced pathways. The pathophysiology of psoriasis involves RORC (retinoic acid receptor-related orphan nuclear receptor gamma) as a critical transcription factor for the development of Th17 cells. FDA has approved an antibody Secukinumab® targeting TNF-α for the treatment of psoriasis. Other FDA approved drugs are Tremfya® targeting IL23 for treatment of moderate to severe plaque psoriasis and Taltz® that blocks IL17 for treatment of plaque psoriasis.

Metadichol® a nano-formulation of long-chain lipid alcohols derived from food is a TNF-alpha inhibitor and also binds to Vitamin D receptor (VDR) that could have beneficial effects on Psoriasis. VDR modulates Th1-mediated inflammatory disease like psoriasis. We now present evidence that Metadichol is an inverse agonist of RORγt and AHR (Aryl Hydrocarbon Receptor) thus controlling Th17, IL17 and IL22. Being a TNF-alpha inhibitor, it can control IL23 thus blocking the significant pathways that exacerbate psoriasis. We present case studies of 7 patients afflicted with psoriasis and skin related conditions and how treatment with Metadichol resolved the underlying disease. Metadichol® has properties that allow its use as a safe nontoxic, toxic solution to combating the growing number of psoriasis cases.

This paper is published in the Journal of Clinical & Experimental Dermatological Research. Citation: Raghavan PR (2017) Metadichol, A Novel ROR Gamma Inverse Agonist and Its Applications in Psoriasis. J Clin Exp Dermatol Res 8: 433. doi:10.4172/2155-9554.1000433 This is an open access journal.  Link Prr-Psoriasis-paper

Most diseases are connected through a network that is commonly called network pharmacology. The paper shows how Metadichol affects many different diseases through this network. It is definitely worth your time to look at the paper. Presented are seven case studies with psoriasis resolved. Picture here is whole body psoriasis that is resolved in twenty-four weeks. The participants used the spray orally and applied it directly to the areas of concern.

pic psoriasis

Other than Metadichol, I do believe that the over the counter ointment of vitamins A and D is the best. Metadichol appears to work along pathways for A and D.  Typically, vitamins are currently recommended at levels that are to resolve basic body needs without looking at higher levels for improved health.

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New Nutraceutical, Metadichol® – Breathtaking Results!

“One good nutraceutical can wipe out the drugs.” Dr. Stephen De Felice

As a regular reader, you have seen several post of the new form of policosanol as a small droplet emulsion, brand name, Metadichol®. (Historic Breakthrough in Health – A Natural Alternative to Vitamin D) This natural substance appears to present a new model for how healing should occur in the body. As a natural substance formed on sun splashed portions of plants, it appears to act in the body very similar to vitamin D. This is a claim in the one of the many patents covering Metadichol®. As you know, you cannot patent a natural substance; however, the novelty is the small droplet that easily absorbs into the body and blood stream where it can become active in cells.

Some of the claims in the patent for healing are as follows: malaria, acne, eczema, ganglion, lipoma, MRSA, wound healing, fungal infections, psoriasis, hair growth, wrinkles, kidney disease, regulates glucose, insulin resistance, Diabetes type 2, Cholesterol, improved lipid profiles, hypertension, kidney disease, heart disease, reduced protein oxidation or oxidative stress, TNF a – significant immune system function, and increases serum vitamin C.

This product has only been on the market since the last part of 2014 in Southeast Asia. The reports coming from that area are amazing in the variety and healing of many diseases. The amazing thing has been no side effects. Of course, since it can be found of most foods, there should be no side effects. This appears to fall into the first rule of medicine, do no harm. When I was first approach by the discoverer, I thought – yeah, yeah another nut found a way to make money. Now after two months, I am truly amazed at the results from my own experience.

My own experience was first the amazement that the pain from my wife’s shingles went away in just a couple of days. It is interesting to note that her primary care physician had identified the rash as shingles along the C3-C4 dermatome. My wife has experienced shingles before that went on for over six months. After four weeks, there was still some redness and my wife went to see a dermatologist who is a friend of the family (I may have instigated this visit because of my prior communication with the dermatologist about Metadichol®). The dermatologist said that it was not shingles, primarily because it had gone away so fast and the apparent appearance of the remaining rash. She described it as a rash of unknown origin. I suspect this type of healing is unfamiliar to the dermatologist.

As for myself, I had a hemorrhoid that shrank overnight after an application of Metadichol®. Also, I treated a wound that I had received from cutting wood. It healed very quickly without a scab formation which I found extremely interesting. After about four weeks of using Metadichol®, there were red formations on my arm and leg. They appeared to be like large pimples or a formation of a colony of bacteria that looked similar to the appearance of MRSA that I had five years ago. After a few days of treatment with the Metadichol®, the redness disappeared. I now wonder if these areas were not colonies of pathogens trying to escape from the action of the Metadichol®. Also, the lipomas are shrinking on our 13 year old dog. We simply spray a couple of sprays on her food every day. We tried to treat a lick granuloma on the dog’s leg. This appeared to work well for a couple of weeks, but the dog started to lick again and the inflammation still exists. We have not tried to increase the dose for the dog. Also intermittent treatment may be an issue as well.

The mechanisms for how the substance works is not truly understood. Dr. Raghavan, the discoverer believes that there is some form of communication that appears to give intelligence to the action of Metadichol®. He has tried the formulation with synthetic components of policosanol and it does not work. He believes that it may be plant and microbial DNA that gets extracted along with the policosanol. It would be interesting if the Metadichol® is also renewing the health of our microbiome and homeostasis is reached in the body through this symbiotic relationship. The consideration of how it may possibly work because of DNA that comes over is daunting when considering the amounts of GMO foods that we are now consuming.

There are to be publications about Metadichol® that will appear over the next several months. This will include information on how our genome reacts and treatment of some very serious diseases. It will be interesting the response of the medical and research communities. – Pandemic Survivor

“Human subtlety will never devise an invention more beautiful, more simple, or more direct than does Nature— because in her inventions, nothing is lacking— and nothing is superfluous.” Leonardo da Vinci