Monthly Archives: February 2019

Medicine…Money…Economics…Ethics

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Health or WealthWhich of the above is more important to you? Are great economics with poor health your desire. Is it okay for the most elite scholars to avoid ethics so that they and the institution they work for have a better opportunity for wealth? We, as Americans, have paid for the research on vitamins and minerals and food (VMF). Yet, the value of VMF is hidden from us for the sake of a robust economy.

All the above are inexorably intertwined. There cannot be a large medical economy without a large sick population. Many have coined the word “sick care” for the present state of healthcare in the US. Drugs and cutting are the typical treatments for chronic disease. Disease that could be treated with VMF. If you had proper VMF before you age, then most likely, you would never reach the state of chronic disease. You would simply age and then with a few months of illness, you would pass. Please read Looking Good, Feeling Better for a better understanding.

Many researchers have not published the benefits of VMF in the hopes of being able to make an analog (prescription drug with side effects because it is not natural to the body) of the VMF for profit. We cannot point our finger at any one institution and say that they are at fault. We are all at fault. Government for allowing institutions to profit from illness while cures in VMF exist. Americans for allowing our government to get away with it in a democratic republic. In our Declaration of independence are the words— “life, liberty, and happiness.” Where is the happiness when you are in so much pain from chronic disease that life is miserable? Are you really going to turn to opiates for relief?

We hold doctors up as being the final decision makers for health. This is not the case. Let me state that again. Doctors are not responsible for the interpretation of the science of medicine. They must follow the medical guidelines as set up by the Agency for Healthcare Research and Quality. AHRQ takes its lead from the Secretary of Health and Human Services and ultimately the President and Congress. Do you think that HHS has your best interest in mind for life, liberty, and happiness? They operate by the principle of “markets before mandates” as clearly stated by Secretary Michael Leavitt in 2008. Note that to value life is the very last. The economy is more important than your health and consequently your happiness.

The archived site that stated these principles has been taken down. Here are government’s nine principles for taking care of your health:

  1. National standards, neighborhood solutions
    2.      Collaborations, not polarization
    3.      Solutions transcend political boundaries
    4.      Markets before mandates
    5.      Protect privacy
    6.      Science for facts, processes for priorities
    7.      Reward result not programs
    8.      Change a heart, change a nation
    9.      Value life

Do you need to have a robust economy for happiness? The government believes so. Is this where the institution of government is more important than the individual it serves. Isn’t this the very definition of evil? M. Scott Peck in his book, “People of the Lie,” uses the Me Li massacre in Vietnam to explain this very point. The squad was given the command that it must survive at all cost because of the importance of the mission that lay ahead. They went into a village with this understanding and proceeded to kill anyone that posed a treat including defenseless women and children.

Instead of bullets that kill you instantly, the institutions that profit use a disinformation playbook that has been around for years or least since WWII when the government sued seventeen multinationals for conspiracy for manipulation of vitamin D pricing and amounts in over the counter supplements. Dr. William B. Grant has published his version of it at Orthomolecular.org.

(OMNS Oct 1, 2018) A “Disinformation Playbook” has been used for decades by corporations to delay government action on matters of public interest that would adversely affect their income and profit. Some well-known examples include the big tobacco companies, the coal and oil industries, the sugar industry, and the National Football League. The Union of Concerned Scientists has outlined five “pillars” of the Playbook [Disinformation Playbook], [Alvord 2017]. Big Pharma may be using the Playbook to slow the adoption of strong support for vitamin D. This article is the product of my further analysis.

The Disinformation Playbook
1. The Fake
Conduct counterfeit science and try to pass it off as legitimate research.
2. The Blitz
Harass scientists who speak out with results or views inconvenient for industry.
3. The Diversion
Manufacture uncertainty about science where little or none exists.
4. The Screen
Buy credibility through alliances with academia or professional societies.
5. The Fix
Manipulate government officials or processes to influence policy inappropriately.

William B. Grant published a paper in 2009 called “In Defense of the Sun.” In the paper he shows that by just raising the level of serum vitamin D (25OHD) to 45 ng/ml, 400,000/yr. premature deaths could be stopped in the US. That is just vitamin D. What about the rest of the vitamins and minerals that we are deficient—vitamin C, magnesium, iodine, organic sulfate, zinc, vitamin B12, folate (not folic acid), and omega 3 fats. That is just the beginning of health. When is science going to admit that the placebo effect or the mind/body connection is just as powerful as most drugs that are on the market? Living longer and feeling better should be our goal. Otherwise, a strong economy is just that and cannot bring happiness because of illness. –Mark Pegram

Pathogen Uses of Cloaking Devices Disrupted

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Pathogen CloakingIn the much-watched Star Trek program, the dastardly Klingons would cloak their ships so that they were invisible to the USS Enterprise. In the human body, pathogens also cloak themselves to be invisible, seem like sugar or a food, by using sialic acids. Sialic acids are common on the cells of vertebrates and are the highest concentration in the brain. The immune system will not attack pathogens with sialic acid attached because they appear as a natural part of the human system. Dr. P. R. Raghavan has found that Metadichol, by expressing the CD33 gene, allows binding of these acids so that the immune system can disrupt the pathogen.
There have been many papers published on human healing by Dr. Raghavan that include increase in stem cells, reduction of diabetes, and general well being realized with the use of Metadichol. The finding of the binding of sialic acid with the expression of CD33 and the increase in stem cells explains the healing of wounds quickly when using Metadichol.
Below is a recently published paper by Dr. Raghavan on this topic. Metadichol acts to up regulate or down regulate CD33 depending on signaling mechanisms in human physiology.

Metadichol® and CD33 Expression in Umbilical Cord Cells

Abstract
CD33 also known as Siglec-3 is endogenously expressed in stem cells and is a marker for the myeloid lineage of cells. Increased expression of CD33 thus allows it to bind to any Sialic Acids (SIAs). These acids are binding sites for pathogens and toxins. By binding to these acids, CD33 can prevent invasion of hosts by these pathogens. Down-regulation of CD33, increase the release of the pro-inflammatory cytokine TNF-α by monocytes that increases reactive oxygen species that are involved in diseases like diabetes mellitus, Alzheimer’s, cardiovascular diseases asthma, and in various cancers.
     The up-regulation of CD33 using Metadichol® was studied using Wharton’s Jelly Mesenchymal Stem Cells (MSCs) isolated from human umbilical cord and were grown in p-35 dishes until confluent and treatment was carried out with different concentrations. One dish was untreated and considered as control. The treated and untreated cells were analyzed using Flow Cytometry. The cells treated at 100 pg of Metadichol® has shown the highest increase (>400 fold) in CD33++ expression (48.77%) compared to untreated control (0.11%).
Link to paper: CD33-paper
This paper may be difficult to digest. However, that should not stop you from using Metadichol for whatever ails you. This is a link for the 29 articles with links to Dr. Raghavan’s papers that I have published on Metadichol.  –Mark Pegram

Vitamin D Treats Liver Disease

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Liver PicVitamin D does treat liver disease. Way back in December 2009, I wrote about how vitamin D had brought myself and one other family member’s liver markers into the normal range. This included a problem with hepatitis—Hepatitis C Cured? By now I have had many tell me that taking vitamin D had cleared up their liver. The commercial that we are constantly bombarded with on TV about you don’t have to have Hep C anymore is a drug that is most likely just a vitamin D mimic or analogue (A manmade molecule or compound that is similar to the natural molecule.).

The Vitamin D Council, Dr. Cannell, has ranted on about how vitamin A is destructive to the level of vitamin D. Strictly speaking this is true. He even had a disagreement with the Weston Price Foundation about the need for vitamin A. Cannell’s contention was that vitamin A build-up in the liver was the cause of chronic liver disease. The truth, vitamin D and vitamin A form a dimer in some of the most important functions in the body. If you are getting enough vitamin D, your liver clears of vitamin A. The important functions that I can think of immediately are cellular differentiation and stimulating the immune system, specifically the start of increasing antimicrobial peptides that are your body’s natural pathogen killer cells. After several months of supplementing with vitamin D, I had to also supplement with vitamin A, retinol palmitate, for the effectiveness of vitamin D. Until trials are run with the combination of vitamin D and vitamin A, there will continue to be confusion over the effectiveness of fat-soluble vitamins. Our forebears were absolutely correct in their supplementation with cod liver oil.

It is the combination of vitamin D and vitamin A that is critical to your health. Our fathers of medicine have long ranted about the dangers of fat-soluble vitamins. The primary reason for this is not a lack of understanding, but the need to sell you pharmaceutical analogues. Eat large amounts of beta carotene as that is not dangerous was the mantra. The truth is that large amounts of beta carotene can be very dangerous to the lungs. The liver does not convert beta carotene until you are already deficient in vitamin A. The manufacturers of vitamins have reduced the amount of beta carotene that was in multivitamins.

Now with nutraceuticals that are available, we can have our cake and eat it too. Dr. P. R. Raghavan has created the nutraceutical Metadichol. This works to bring the body to homeostasis. It works along many pathways included genetic expression and control of the molecular receptors. What is Metadichol and why is it so effective in treating disease and healing wounds? Metadichol is made of policosanol that is commonly found on all plants. The problem in modern nutrition is that we take away the part of the plant where the concentration of the policosanol is the highest. The advantage of Metadichol is it is made by making a small particle emulsion. We did some of this on our own when we used to chew the husk from food. Now, we have the opportunity to assure that we are getting enough policosanol for health. Taking policosanol as a supplement is not the same as the small particle emulsion. Dr. Raghavan has published over ten papers on the matter and is going around the world to lecture and help other researchers understand the importance of the small particle emulsion of policosanol. Metadichol is very important in how it puts the vitamin D receptor into the state that is required for health. The vitamin D receptor is like the conductor of an orchestra in the smooth harmonies of all receptors. Here is a recently published article on how Metadichol is significant for liver disease.

“A Multi Gene Targeting Approach to Treating Liver Diseases with Metadichol®”

Abstract

Liver diseases are becoming a major health concern. In the developing countries it is due to microbial infection. In the rest of the developed world it is due to alcohol abuse. Chronic liver disease and cirrhosis are a significant health concern in western countries. It is the fifth most common cause of death, after heart disease, cancer, stroke, and chest disease. The liver is capable of regeneration, but it can be overwhelmed leading to liver diseases like cirrhosis and hepatocellular cancer (HCC).

Vitamin D levels are low in most patients with liver diseases, and this suggests possible therapeutic benefits with use of vitamin D or its analogues. Vitamin D, through the vitamin D nuclear receptor (VDR) plays a crucial role in mineral ion homeostasis. The liver has a central role in vitamin D synthesis and there is a need for an agent that will not lead to hypercalcemia. Metadichol, a nano-emulsion of long-chain alcohols derived from food, is an inverse agonist of Vitamin D can fill this void.

In Diabetic rat studies, it inhibits TNF alpha, ICAM1 (intracellular adhesion molecule), CCL2 (chemokine C-C motif) also referred to as monocyte chemoattractant protein 1 (MCP1). All these cytokines, chemokines are known to have important role in liver diseases. We show that Metadichol indeed does work in liver disease patients by normalizing essential liver enzymes ALT, AST and ALP, and GGT. This approach is an example where Metadichol targets multiple genes and via multiple pathways to bring about homeostasis of the liver and is a useful, safe, nontoxic product in treating liver diseases and alleviating a global threat.

Link to published paper: Liver-disease-paper (1)

Mark Pegram

Please note that I have not been writing due to the long-term illness and recent death of my brother from agent orange exposure during his thirty months at war in Vietnam. The mutation of his genes from the dioxin exposure prevented his physiology from reacting normally to modern medicine and nutrition. Interestingly, the doctors and researchers in my family have agreed to this. War and the aftermath is hell.