Heart Disease, Cholesterol, and Vitamin D3

I have written several post of vitamin D and heart disease and there is so much more.  There is an exciting article about heart disease and the effect of vitamin D at WebMD.

By Dr. Michael Richman, MD, FACS on Cardiovascular Disease and Vitamin D.  Part 1 and Part 2.

As we begin our plunge into vitamin D winter then heart disease that has been arrested by getting an adequate amount from the sun will become more active.  As you can see from this Harvard news article, it is important to start supplementing with vitamin D.  However, here again we find that mainstream medicine is too conservative in the amount of vitamin D.  It is better to follow the directions from the home page of the Vitamin D Council to assure that your level of 25(OH)D3 is above 50 ng/ml to have the best effect on heart disease and the upcoming expectation of a serious flu season from the H1N1 virus.

As we have discussed in other post, vitamin D is made from cholesterol.  So the marketing of statin drugs and their use in lowering cholesterol may not be beneficial to your health.  The article, “Vitamin D is Synthesized From Cholesterol and Found in Cholesterol-Rich Foods” by Chris Masterjohn from May 2006 will give you a better understanding of how this works.  His comments on vitamin A are also important to the understanding of how A and D work together in your body.  Here is the research page from the Vitamin D Council on heart disease.

Going into the sun is not enough if you live above about 35 degrees North latitude after September.  Start supplementing to the directions of the Vitamin D Council.    – Pandemic Survivor

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Heart Disease and Diabetes

As you may already know, the insulin surges that occur when you are diabetic cause a significant amount of plaque to build up in the arteries.  It seems that insulin surges for whatever reason are the cause of this unfortunate course of the disease.  There is hope however that this does not have to be the course of the disease.

You can read the paper, “Human serum 25-hydroxycholecalciferol response to extended oral dosing with cholecalciferol” by Heaney et. Al with an explanation of how blood sugar and insulin is blunted once your serum 25(OH)D is above 32 ng/ml.  It is an open source paper and I would suggest that you read the full paper if you are diabetic or at least have your doctor read it. From PubMed

Also ‘The Vitamin D requirement in health and disease’ by Dr. Heaney.

Dr. Joe Prendergast of California has a long time practice of endocrinology.  He has treated many diabetics and has had great success in reducing the amount of heart disease in his practice.  Dr. Prendergast discovered in the early nineties that he had a significant amount of heart disease.  His father had died at an early age of this disease.  He decided that he was going to do all that he could not to follow the same course.

He contacted Dr. Victor Zhu who is was head of research at that time at Stanford University to see what he was doing about heart disease.  Dr. Zhu set him up with one of his research fellows that was testing mice with arterial plaque.  Dr. Prendergast decided that he was going to try the same course of treatment that had proved to clear the arteries of the mice.  After a number of years he was imaged again for another purpose and it happened to be the same radiologist.  The radiologist discovered that Dr. Prendergast arteries were clear.  They checked to be sure that the patient file had not been substituted that indeed it was Dr. Prendergast that showed no arterial blockage.

Dr. Prendergast who was at one time head of the board of endocrinology for California decided that he was going to treat the diabetics in his practice.  He has treated over 4000 patients.  The heart disease had reduced to such a low rate in the small city between San Jose and San Francisco that the three man cardiologist practice closed and move to another town.

It seems that he treated his patients with a combination of vitamin D3 and l-arginine.  As you may know there was a Nobel Prize for Physiology or Medicine 1998 awarded for the understanding of the communication pathways for nitric oxide, NO, and how through its signaling pathways it affects the function of the arterial wall cells.  This is what happens when heart patients take nitroglycerin.  However the NO is released in a lower amount when using l-arginine.

It would seem that with such success that this practice would have been adopted by all the doctors treating diabetes.  The vitamin D3 does it thing with the genetics, insulin control, blood sugar control, and the all the other good benefits.  Dr. Prendergast has even written a book about his success in using nutrition with his patients, “The Uncommon Doctor.”

But you know, you do not have to take my word for it.  The owner of Apple Health, David Stouder, was so fascinated by the number of people that were coming to his store to buy vitamin D and the success that they were having in the course of their disease that he decided to interview Dr. Prendergast.  You can go hear the interview at the website set up specifically for that purpose.  www.nutriphobia.com (writers note October 17, 2009 – Unfortunenately this interview has been taken down and I was unable to find it on the new website.  Here is his video comment at youtube )  The first six audios are simply about overcoming the fear of vitamin D and the button ‘click to hear Dr. Joe Prendergast’ is the audio interview with Dr. Prendergast and the above story.  I know that if I were diabetic, I would have my doctor get in contact with Dr. Prendergast for a consult at his practice Endocrine Metabolic.

If you have heart disease or diabetes I would certainly hope that you would spend some time in reviewing this understanding and get your doctor involved.  It is not only your life but it is the life of each patient that your doctor chooses to treat.

In the main time – GO INTO THE SUN!  – Pandemic Survivor

Heart Disease and Vitamin D3

I will spend some time in talking about vitamin D3 and heart disease.  In the maintime you should just go read Dr. William Davis at the Heart Scan Blog.  He is a cardiologist from Milwaukee that has this vitamin D thing and heart disease figured out and is treating his patients with diet and nutrition.

Dr. Davis most recent post is about D2 and D3 and how D3 is so much more efficaious than D2.

Here are all of his post on vitamin D.  He has 67 post of vitamin D so I will not be able to compete with that but will try to provide you with a summary.  In the maintain just go read and it will be a real education for you.

If you have heart disease then you definitely need to spend time with Dr. Davis.  GREAT job Dr. Davis!  I know that you have saved many lives.

– Pandemic Survivor

Thinking about Cholesterol

Let’s just stop for a while and do some critical thinking about cholesterol.  I am not bound by having a medical degree or much education in the biological sciences.   This frees me from boundaries that are typically imposed when trying to come up with a new theory or hypothesis.  There are just about always these preconceived notions about how a process works that stops researchers from considering other pathways or avenues or even superhighways though they are clearly marked.  Of course this is really good for the keepers of the cash cow.  With that out of the way this makes it possible to allow my imagination to run free without restraint.

Okay so researchers, maybe you should pay attention to what I am about to say because some day it may make you a super star if you pursue my line of thinking.  However, if you work for one of the companies that make statin drugs and start talking about what I am proposing then you better put your things in a box and start looking for a new job.

So what is cholesterol?  It has the word sterol in it so that most likely makes it a fat.  So what do we know about fats?  They are necessary for life because I remember the story about the arctic explorers that had this canned food that was primarily carbohydrates and protein and they started to get sick and bloat.  It was later discovered that you have to have fat to survive.  It has also been discovered that we do not need carbohydrates to survive but this battle still rages on.  We do know that low fat foods that have the fats replaced with sugars or other carbohydrates just make us fatter.   I have proved this over and over by the amount of weight that I gain when I eat low fat foods.  And on top of that, the low fat foods just make me want to eat more.

Now there have been all of these stories about how cholesterol in the blood causes your arteries to clog up with plaque and this stops the blood flow.  When your blood does not flow for more than about five minutes you die and this is not good to a long life.  I have read studies that say that too much cholesterol causes this plaque problem and heart disease.  I have read studies that say there is no correlation between cholesterol and heart disease in more recent literature.  It was suggested that since a high amount of cholesterol would cause heart disease and that since cholesterol is fat that we eat too much fat and this causes us to have heart disease.  This seems so counter intuitive to the understanding about the explorers that did not get enough fat.

We can just put all of that aside and say that cholesterol is a marker and not necessarily a cause and effect for heart disease.  Now what does being a marker mean?  Well it means that a certain thing is an indication that something will happen.  It is like the speed indicator in your car.  If it says that you are going 70 mph that the car is going very fast and all the physical things that you can expect to happen at this speed will happen.  The speed indicator is not the cause of the car moving at this speed.  The indicator only says that the car is going at this speed.

Now, when I had severe back pain and my vertebral disc were failing and I had sleep apnea, I had very high cholesterol readings.  I had one test that indicated that my cholesterol was over 240.  The test also said that my fasting triglycerides were 680 or extremely high.  I also had problems with my heart because I was having pre-ventricular contractions and one time even a sudden fast heart rate.  My heart rate went over 200 bpm and stayed there for over 15 minutes.  I was in so much pain from the pressure on my spinal cord that I just thought that maybe this was it and I would just die and get rid of the pain.  However, my heart slowed down and I was just fine except for the severe continuous ever hurting downright destroying evil pain – pain – pain.

Then I started taking vitamin D3.  My spine healed.  My sleep apnea went away because the nerves for the lungs and throat were free to do what they were supposed to do.  My heart started working just fine.  My energy returned.  My brain healed.  My mind cleared. And guess what else happened.  That’s right on my last blood test, my cholesterol was 175 and my fasting triglycerides were 72.  Now how could this be because since I have been out of pain I eat the worst diet ever.  I am still overweight (BMI 130) even though recently my metabolism seems to be speeding up and I have lost 10 lbs in the last month. I eat now because I can because there is no pain when my gut gets big unlike before when my spine was shot.  So why would eating cheeseburgers and french fries and milk shakes cause my lipid profile to improve?

Thinking about arterial plaque, I have recently read that this plaque is a very small percentage of the gooey stuff that holds it together from cholesterol.  It is mostly calcium dross.  I like the word dross because that is what forms when you get too much oxygen over molten metal and so this is what happens in the arteries and not the veins where the oxygen is low.  Too much oxygen in the arteries causes the calcium in the blood to form dross.  This makes about as much sense as what we have been told about how the fat causes our arteries to plug.  If it was just fat, then the veins would clog as well.

So following the logic of the ‘eat low fat’ people, we should just stop breathing as this would not allow oxygen into the arteries and cause dross to plug them.  Now you guys that majored in the biological sciences still with me or have I sucked all of the air from your systems?  I know this is way out, but what fun!!!!!!!!!

When reading about how our body makes vitamin D, I discovered that the ultraviolent B radiation on cholesterol in the skin causes it to turn into vitamin D.  This vitamin D along with some isomers and other products like metabolites that it forms makes up our vitamin D physiology.  Now not being hampered by a biological religious cult, I would just think that as our bodies get enough vitamin D to where systems get satisfied that we stop making cholesterol.  When we do not go out into the sun and our vitamin D level gets low, our liver and skin spits out lots of cholesterol and our body starts screaming at us, ‘GO INTO THE SUN’.  We go into the sun and if there is enough UVB then our body makes D3.  We are happy as our pineal gland starts spitting out the commands for all of these happiness squads of hormones that can now act because we have enough vitamin D.

Process of vitamin D being made from cholesterol, University of California Riverside.

This also makes sense from understanding that the plaque in our arteries is a calcium plaque and the primary system for controlling calcium absorption is vitamin D.  If we do not have enough vitamin D then calcium serum regulation falls to the parathyroid hormones like a failsafe system.  We survive and do not thrive.

And while I am thinking about it, I do not believe there is a single case of secondary hyperparathyroidism when the serum 25(OH)D level is above 40 ng/ml in the medical literature.  At least that is what a bunch of guys from Spain have said in 2003.  You would think that knowing how PTH and 25(OH)D work together that we would increase the level of 25(OH)D before we started chopping out peoples parathyroids.  This happened to a friend of mined and he simply increased his 25(OH)D, his serum calcium normalized and he did have to get his parathyroids chopped.

So then, cholesterol is just a marker for low vitamin D levels in the body which means that we need to take action to get the level of vitamin D up so that over 2000 genes can turn off when they are supposed to be off and on when they are suppose to be on.

Changing the cholesterol level to try to prevent heart disease then would be like making the speed indicator on the car read 35 mph when we are really going 70.  We are just looking for an accident to happen because we do not know that we are going so fast because of the artificial indication.  I suspect this is what happens when we take statin drugs which I understand are just bad mimics of the vitamin D feedback system that tells us to stop making cholesterol.  This is really bad because when we do go into the sun we do not have adequate amounts of cholesterol to make vitamin D.  Okay, biological geeks, did you get it?  This is the reason for all the confounded data in your studies because your theories just – well- truly suck!

I say to you, the manufacturers of statin drugs, that I do not believe that you are so bad at logic and biological science that you could get this so wrong.  I think that you had dollars signs in your eyes because you could not figure out a way to profit from healthy people replete in vitamin D.  So it is obvious that you love money more than people even though it is the people, your customers, that is providing you this money.

I suspect that there is enough data out there from other studies that an energetic researcher could crunch around to show that when peoples serum 25(OH)D levels are less than 32 ng/ml that they have a problem with high cholesterol.  Get the levels up to above 50 ng/ml for a couple of months and I would suspect that you would see a significant drop in cholesterol.  It happened to me and others that I know.  Are our bodies just freaks of nature?

It seems that doctors that have tried this on patients with heart disease have had great success.  Why don’t you go visit with Dr. William Davis at the Heart Scan Blog and see for yourself.

Even better –GO INTO THE SUN!!!!!!!!!!!   – Pandemic Survivor

Healtcare Reform – Heal the People

Sorry to not have posted in a while.  I had vacation and business to take care of.  I am trying to post two to three per week.  Send me your vitamin D3 survivor stories to email vitamindmark@gmail.com.

I have been truly amazed at the amount of misinformation that is thrown about during the debate over healthcare reform.  There are both good and bad parts of the legislation that is being proposed.  I believe that it is good if we can get to a health coverage that takes the enormous profits of the health insurance industry out of play and how the intent to profit negatively impacts health.  I do not believe that the government taking over these profits as another form of tax is proper either. On the other hand the intrusion of government into our private lives can be devastating.

As I was surfing the channels listening to the comments by various ‘news’ channels I found Bill O’Rielly and Dick Morris talking about one of President Obama’s recent speeches on the mater.  They were just about to end the segment when Dick Morris made the comment that Canada’s death rate from cancer was sixteen percent higher than the US.  “Why would we want a healthcare system that would cause this much higher death rate”, he said.  Bill agreed and they ended the segment.  I decided to follow this line of argument.

I found the total death rate from all neoplasms or ‘new growth’ to be 184 deaths per year per 100,000 in the US  for 2005.  From Reuters. I did confirm that that Canada’s death rate from cancer was about 16% higher.  In following the logic of modeling a country with low cancer death rates, I then looked at Mexico.  I found the death rate to be about 90 per 100,000 or about half of what the death rate was for the US.  Article in the Oxford Journals.  This is about half the rate as the US so we most likely would want to adopt the healthcare industry in Mexico?  Dick Morris, get a grip!  Fear mongering is not the answer to healthcare.

I then looked at the death rate from all causes from the CIA  data to follow Dick’s logic in how to discover a healthcare system that is most appropriate.  I found the 2009 est. for the US to be 8.3 per 1000 with a worldwide rank of 102.  I also found the death rate in Canada to be 7.74 per 1000 with a rank of 117 and Mexico at 4.8 per 1000 with a rank of 194.  The highest death rate with the number 1 rank is Swaziland at 30.8 per 1000 and the lowest was the United Arab Emirates with a rate of 2.11 per 1000 and a rank of 223.

Now what are we to make of this?  It is to be noted that the lowest death rates in the world are primarily in countries that are awash in sunshine.  Countries in the Middle East are highly populated in the lower rankings as well as countries along the lower latitudes, closer to the equator, in the world. Swaziland at the highest is totally understandable because it has been devastated with the HIV virus.  It is also the world’s last absolute monarchy which means that if you do not do what the government wants you die.  With the amount of war going on in the Middle East, it is surprising to find the deaths rates so low.  However, think of how these countries have so many days of no clouds and just bright sunshine.

Let’s think about Mexico.  Mexico City has the highest population of any city in the world at almost 9 million.  It is also located at approximately 7400 ft in elevation.  This puts it above a lot of the atmosphere that blocks out UVB waves that generate vitamin D in the skin.  As an aside it was the practice to build solarims for the treatment for TB in the first par of the first part of the 20th Century above 5000 ft.  As we have discussed in other post, vitamin D3 has a vector in the pathology of all disease.  It is interesting that the death rate from the H1N1 virus has been so high in this country.  However, in general as the H1N1 has spread the countries with low vitamin D levels have much higher death rates from this disease.

Could it be that Dick Morris is just wrong in his statement?  I think that the answer is absolutely yes.  What should we do for the health of the population?  The best answer for healthcare reform is to treat the populations of the world with the best available science.  That is to be sure that everyone’s serum 25(OH)D3 level is above 50 ng/ml.  As discussed earlier from a paper by Dr. William Grant of SUNARC.ORG the serum level of people in a sunny country is 54 ng/ml to 90 ng/ml.  This could be done for about $20 dollars per person per year.  What an inexpensive way to improve the health of all people.  For the US this is only 6 billion dollars per year.  I suspect that this is going to be significantly less than we spend on the H1N1 vaccine alone for this year.  It is also just a ‘drop in the bucket’ of that 2.5 trillion dollar US medical economy.  But here lies the problem.  The medical economy could drop by 30% if we healed the population and what would we do with all those lost insurance jobs.  I would not want to be president, but if I were, normalizing the serum 25(OH)D3 level would be the first thing I did.

Spend time in the sun!!!!!!!!!!!!!!  – Pandemic Survivor