Discovery of the Century—Healing Cartilage

Cartilage damage is the number one problem that creates pain in the aging population.  Cartilage compresses, nerves compress, and pain and chronic disease is the result. Unfortunately, it has also become a problem with the not so aged.  If you are a reader of this blog, you know of the back and nerve pain that I suffered for three decades.  I even wrote a book about the recovery, Healed from Chronic Pain.  I have been in the process of writing a second book about how to repair cartilage and felt that something was missing.  The missing environmental factor is the SUN.

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I started to supplement with vitamin D3 November 4, 2004.  I had shrunk an inch from degenerative disc disease over the years.  When I combined the supplements that I had researched, my cartilage repaired.  Not only did my cartilage repair, but also my health overall returned.  I had always assumed that getting vitamin D3 from whatever source was one of the keys.  That is, keeping my serum vitamin D (25(OH)D) above 60 ng/ml.  However, I noticed at times that my cartilage had not rehydrated to keep me at my new height.  During the year of recovery, I had grown back to my original height in the first seven months.  During the next three months, I grew to my genetic height of–-an inch and one half taller than I had ever been.

It took me several years to find one key necessary for cartilage repair.  During the year of repair, I had supplemented with methyl folate, as I had read that it crossed the blood brain barrier.  I knew that my brain had shrunk from over a decade of chronic severe pain.  I thought the methyl folate would help my brain repair.  I now realize that the methylation cycle, with methyl folate and its cofactors, were necessary to stimulate stem cell growth.  Only fifty percent of the population can convert folic acid, a manmade molecule, to folate required to drive the methylation cycle.  Thanks to Dr. Ben Lynch, I now understand how important the methylation cycle is to health because of its role in genetic expression. (Note: betaine or trimethyl glycine will allow the methylation cycle to work without folate.  The human body is so smart in usually having two pathways.  Both folate and betaine are in spinach; Popeye was so shrewd!)

The other key that I did not understand, at the time, was sulfate.  Sulfate is critical to health, and here. If you think of all the healing remedies that were about soaking in mineral baths, sulfate and magnesium ( and here) were always key factors. I supplemented with large amounts of chondroitin sulfate and glucosamine sulfate during the year of healing.  I now realize that these molecules are so large that you most likely do not absorb them.  However, I think the sulfate from the molecules is absorbed.  This is especially true if you have a higher vitamin D3 level as vitamin D controls the transport of sulfur through dermal layers.  I now use MSM as a sulfur supplement as well as eat cruciferous and allium vegetables.  Both vegetable groups are high in sulfur, especially the garlic, onions, and leeks.

The “event” happened this past fall to bring to light the last missing component that is necessary for cartilage repair and hydration.  I had oral surgery in October for a granuloma that had developed over long amount of time per the surgeon.  I had noticed an issue with the tooth that I had a root canal done in the ‘90s.  The surgeon said there was an opening in the root crest that was allowing bacteria to destroy the bone.  In any case, this prevented me from doing my normal routine of using a tanning bed in October.  By the first of November, I started to get a nerve rash on both legs.  I had experienced this before and knew that it was coming from compression of my disc.  I measured my height, and sure enough I had shrunk. I recovered my height in two times of tanning in one week.  The nerve rash disappeared and the severe itching stopped.

The three months that I grew to taller than I had ever been was during the summer.  I spent at least thirty minutes with the midday summer sun on my back.  It has now become obvious to me that the sun is critical in three ways.  The formation of vitamin D sulfate, formation of cholesterol sulfate (Dr. Stephanie Seneff and here), and improved formation of the exclusion zone (Dr. Gerald Pollack) at the cell membranes. I will not pretend to understand the biology involved, but know that this helps to hydrate and repair cartilage.

Through the grace of God in my medically untrained ways of thinking about how to reduce pain and repair cartilage, I stumbled on the significance of vitamins and minerals and environment.  Cartilage repair is complex and that is the reason that medical science has misdirected us, I hope.  I think specialization has kept us from putting it all together.  Vitamins and minerals that I was taking when my cartilage healed–-all the vitamins as supplements and mineral complexes. The source of the manufacture and the dose of the vitamins and mineral supplements is critical.  With modern processed foods, I would have to eat about 8,000 calories per day to get an adequate amount.

Critical supplements for cartilage repair: Vitamins A (used cod live oil), B (methyl folate and its cofactors), C, D3, and possibly E; magnesium, zinc, iodine, selenium, manganese, calcium, and sulfate; and environmental exposure to UV light and infrared light. Proteins from bone and skin are also critical (gelatin-simple explanation).  The dosage is key to this combination.  Too much or too little of any of these items will trip you up.  Through trial and error, I have arrived at the correct combination.  I will now begin the rewrite of my book about how to heal cartilage. I have had many people to try my formula with great success.  The ones that regularly exposed themselves to the sun were the most successful.  –Pandemic Survivor

©2017 Mark Pegram

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Time for Action to Help Relieve Pain

I started to write this blog in 2009. That was five years after I had recovered from chronic severe back pain. I had written a non-published book at that time about the experience of healing. The book was about my two back surgeries and how I avoided the advice of doctors for more surgeries. This original book was a flow out of all that I had experienced. Three decades of chronic pain, two failed surgeries, the discovery that I could heal back pain with nutrition and growing three inches taller in ten months as I healed (think about twenty plus discs expanding in height more than one tenth inch to clear all the nerve roots). I have finally gotten over my thinking that the medical profession would move forward and not allow people to continue to suffer with back pain. After all, if an engineer could figure the combination of nutrients to allow cartilage to heal, then certainly someone in medical research could do the same.

I struggled after healing that first two years with why the medical guideline changes for healing failed cartilage had not already occurred. I had met twice with my congressman about the possibility of Congressional hearings to allow the experts to speak on things they had found on nutritional deficiency and chronic disease. We had talked about a meeting with Senator Burr to see if we could make it happen. Then, I discovered Secretary Michael Levitt’s Principles for Health and Human Services. With “Markets before Mandates” five positions above “Value Life”, I knew the economy is more important to the US Government than any life of an individual or many individuals. I knew that only a grass roots effort would cause change. I was happy to see Carole Baggerly turn her anger into action with the founding GrassrootsHealth. If you did not watch her in my last post then do that now! Presentation to Direct-MS Canada.

I have finally gotten over my emotions enough to act. I took an online course in creative writing, a daunting task for an engineer. I have reduced that first two hundred page book into about one hundred fifty pages and plan to e-publish within a week or so. It is about my life of pain, the discovery of healing, the healing, social acceptance, and my struggle to understand what was happening in government and our institutions. I only tout vitamin D3 in this book, but understand that it is the combination of many nutrients that allows cartilage to heal. Also, I wanted to wait because of the possibility that I was a unique case.   But after ten years of enjoying good health, it is now time to act.

I am about seventy percent through writing a how to book on healing back pain(still working on finding a publisher). This book will include a section on how to manage pain, the nutrients required for healing, and how to work with your doctor as you use nutrients to heal. To accomplish this task, I have persuaded a couple of medical professionals to coauthor, Molly Schneider, PharmD, and Caitlin Gerrald, PA-C.  Also, my primary care physician has agreed to write a preface supporting my claims of healing. We will also have a chapter for physicians. Here we will try to describe the physiological mechanisms as we best understand them to get physicians to understand the multiple levels of DNA/RNA action and needed nutrition to support them. We will also help physicians avoid the pit falls like just supplementing vitamin D versus checking the blood serum level of 25(OH)D.  Also supplementing with vitamin D3 versus vitamin D2. We will also do the same with other nutrients that are on the market as mimics or analogs of natural supplements. I am asking several of the people that have tried the supplements to be interviewed for this book and to discuss their outcomes. Hopefully, I will be able to release this book within six months to a year.

How significant is the need for a method to heal back pain? Consider Dr. Mercola’s recent article of “How to Avoid the Number One Cause of Disability”

My doctor, after the second surgery, offered to write me a letter for seventy percent disability. I declined at the time because through faith I believed there was a solution. It turned out to be both medical, environmental, and nutritional. Everyone who has suffered with back pain should at least try the nutrients before attempting the surgery route. Dr. Mercola makes this statement in the summary: “I strongly recommend avoiding surgery until or unless you’ve exhausted other treatment options, which include chiropractic, massage, acupuncture, exercise, and most importantly, K-Laser treatment.”

I would here like to apologize to all the people in the world suffering from chronic pain for not releasing these two books earlier.  Also for not disclosing all the needed nutrients in a timely manner. Unfortunately, there is more than physical disability in suffering with chronic pain. It totally distorts your outlook and mood from decades of pain and drugs. Every time I would hear of another person dying from chronic disease from apparent nutritional deficiency, I would allow anger to raise its ugly head instead of using it for action of love, peace, and joy. Here is a video of a recent Toastmasters speech in which I describe an event with one of my neighbors.

“Pulled from the Abyss Again”

I would like to thank my wife for her help in this effort and all the pain and suffering she has had to witness without a flinch.  – Jill W. Pegram, MT(ASCP)SC

Popeye Ashamed of his Government

Popeye always saved Olive Oyl from the dastardly Bluto with the help of spinach.  It was thought at the time that the iron in spinach was the key to its ‘super properties’ and was promoted through the Popeye cartoons.  However, it is now known that the advantages of spinach are because of the large amounts of trimethylglycine and hydrofolate.  Both of these nutrients allows for the methylation cycle to occur for proper reading of your genetic map.

The FDA is now trying to keep the word folate, vitamin B9, off of labels for supplements.  Only folic acid, the synthetic form, is to be used.  This is an outrage on two fronts.  First, many people’s livers do not adequately process the synthetic form of folate, folic acid.  That is about thirty to forty percent of the population.  This increase of concentration of folic acid in the blood stream is thought to suppress the immune system and has caused an increase in lung, prostate, and colon cancer. Second, over sixty percent of the population has a mutation that reduces or prevents the enzyme, MTHFR, from being made.  This is the enzyme for completion of the conversion of hydrofolate into methyl folate.  Here is the complete story:  Alliance for Natural Health – ” Breaking News: FDA’s Sneak Attempt to Ban Another B Vitamin”

Poor Olive Oyl, what is she to do?  Will Popeye be strong enough to save her by supplementing with a man made molecule that was made in the laboratory in the 1940’s, folic acid?  Maybe a can of boiled spinach followed by a good punch in the eye of that dastardly FDA would do the trick.  Merck and FDA shaking hands to protect a market and create illness so that they can buy fast cars and appeal to Olive Oyl’s adventurous side is much worse than anything Bluto ever did.   “I’m through to the finish ‘cause I eats me spinach, I’m Popeye the sailor man.”  Ah, the days of super heroes when heroes were really super – Pandemic Survivor

You Don’t Have to Shrink with Age

As we age most of us start to shrink in height.  It is not unusual to shrink an inch or more by the time you have reached sixty years of age.  If you have not practiced good nutrition, this shrinkage could even be more severe.  This shrinkage will lead to nerves that are ‘crowded’ as they exit the spine causing an array of symptoms.  Aching and cramping muscles, numbness and tingling, and yes even physical appearance of rashes and dermal reactions.  If not treated with exercise and good nutrition, it could ultimately lead to failure severe compression of the spinal nerves and serious disease states.

A normal part of the experience of living means that during the day a six foot person could shrink as much as three quarters of an inch just from dehydration.  As we sleep at night and take the pressure off of the vertebral discs and hydrate the cartilage between the discs expands.  Then when you get up, most of the soreness of muscles has gone and some stretches makes you feel like a new person.

It has generally been accepted in the practice of medicine that shrinking with age just happens and there is nothing that you can do about.  Of course if you are a regular reader you know that I have overcome this shrinkage.  There is nothing in the medical science about how to heal the cartilage to keep it healthy.  This is largely due to the fact that most trial studies work only one nutritional factor at a time.  However, you can find what nutrients allow for cellular differentiation of chondracytes, cartilage stems cells and the building blocks of cartilage and joint lubricant.  It is a combination of vitamin D, vitamin A, sulfur, magnesium, vitamin C, and iodine.

Determining the exact amounts to use is an art that most be tailored to each individual depending on what they eat.  Of course there is not really much research on is sulfur.  However, the alternative medicine folks have promoted glucosamine sulfate, chondroitin sulfate, and MSM for joint pain.  I believe the body is used to getting its sulfur from sulfate that is found in water as calcium sulfate and magnesium sulfate.  However, with the complaints of the hardness of water affecting the way it cleans and the taste, a huge effort has been made to get the minerals out of water and has led to a significant deficiency.  I suspect the many diseases associated with vitamin D deficiency also have cofactors of the above named nutrients.

If you want to help stabilize your discs, then an adequate amount of these nutrients is an absolute.  You may start using the triple strength products that include chondroitin, glucosamine, and MSM.  Follow the directions on the box at two per day with most brands.  To assure that you are getting enough sulfur, you may want to eat eggs every day and a healthy amount of garlic and onions when appropriate.

The vitamin D along with vitamin A drives the cellular differentiation of the cartilage cells.  It is wise to get your serum level of vitamin D above 60 ng/ml, 25(OH)D.  After about three months at this level, your liver will start to clear of vitamin A.  It is then wise to take about 4000 IU of vitamin A from fish liver oil or eat a piece of liver about the size of your hand once per month.  By following this formula, I got back the inch that I had shrunk and then grew an additional two inches as my genes fully expressed themselves. This happened over a ten month period and was amazing as my eye line changed and my view of the world changed.

Exercise, exercise, exercise, and yoga and inverted decompression are best.  There is no blood flow to your cartilage and the accordion like action gets the nutrients into your joints.  To your healthy discs – Pandemic Survivor