Human Production of Vitamin C

Human C

I had reported early the finding of Dr. P. R. Raghavan for increased levels of vitamin C in diabetes cases when treated with Metadichol. (Metadichol Induces High Levels of Vitamin C) It appears that the increase was activation of the gene responsible for making the enzyme necessary for the completion of vitamin C production.  This was based on the findings of Dr. Raghavan’s gene studies. This is true in animal studies not yet proved in Humans as the GULO gene is non-functional. Does Metadichol activate the dormant GULO gene in humans despite it being mutated? Studies provided by Skanda Life Sciences shows that Metadichol does activate the gene responsible for the missing enzyme in mouse studies. “Metadichol, Vitamin C, and GULO Gene Expression in Mouse Adipocytes” Link to PDF Metadichol-Vitamin-C-Gulo The loss of production for vitamin C in humans and not in other animals is a mystery.

Vitamin C, also known as ascorbic acid, has shown a remarkable ability to reduce disease. Benefits include the prevention and treatment of scurvy, common cold, boost the immune system, lower hypertension, treatment of lead toxicity, cataracts, treatment of cancer, stroke, elasticity of skin, wound healing, and asthma. Metadichol® has shown it can help maintain high levels of plasma vitamin C without oral supplementation of vitamin C. Metadichol® is a nanoemulsion of policosanol or the waxy substance that is found in high concentration on the sunny parts of plants.

Vitamin C is so important to immune health that without it we would soon die of scurvy. Sailors in past centuries developed the disease because of the lack of fresh vegetables and fruits. The British used limes to provide vitamin C and the Germans used sauerkraut (Thus, the associated nicknames). Recently a physician in Norfolk Virginia found that he could treat septic shock (deadly blood infection) with vitamin C, thiamine, and hydrocortisone. The physician has had only one death after treatment of 150 patients. This shows the significance of how important vitamin C is to the immune system, and may explain how Metadichol works so effectively on so many different diseases.

Metadichol boosts the immune system in many other ways. One of the more important ones is how it affects the action of the vitamin D receptors. The vitamin D receptor acts like a conductor of the orchestra for other nuclear receptors. One very important action of the receptors is the making of antimicrobial peptides that are killer cells for all pathogens. Vitamin C supports many of the functions of neutrophils. Neutrophils (white blood cells), another important immune system function, ultimately converts to various types of killer cells that hunt down pathogens.

Vitamin C also has a role in stem cell production as well as collagen folding. This makes Metadichol very significant in wound healing. Treating and preventing infection and acting in wound repair. It is truly amazing how this one substance can act in so many ways. Collagen is useless without folding of the molecule. Because of the folding of collagen, vitamin C is also very important for building strong bones. Thanks for reading­­–Mark Pegram

More Resources:

https://ods.od.nih.gov/factsheets/VitaminC-HealthProfessional/
https://www.nature.com/scitable/topicpage/the-mystery-of-vitamin-c-14167861
Effects of Vitamin C on Neutrophil Function: https://www.ncbi.nlm.nih.gov/pubmed/17235150
Other articles about Metadichol and research papers: https://pandemicsurvivor.com/category/metadichol/  

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Metadichol® Induces High Levels of Vitamin C

Vitamin C, also known as ascorbic acid, has shown a remarkable ability to reduce disease. Benefits include the prevention and treatment of scurvy, common cold, boost the immune system, lower hypertension, treatment of lead toxicity, cataracts, treatment of cancer, stroke, elasticity of skin, wound healing, and asthma. Metadichol® has shown it can help maintain high levels of plasma vitamin C without oral supplementation of vitamin C. Metadichol® is a nanoemulsion of policosanol or the waxy substance that is found in high concentration on the sunny parts of plants.

Post LabelLinus Pauling, a two-time Nobel Prize winner, spent a significant effort in promoting vitamin C in the prevention and treatment of disease.  He was scoffed at by the mainstream medical community. Now, there appears to be better acceptance of using vitamin C to treat disease. It is interesting to note that humans, unlike other mammals, do not make vitamin C. Goats are known to make large amounts of vitamin C each day.  A one hundred fifty-pound goat can make as much as 13,000 mg each day. I typically take one to two grams of vitamin C per day.  If my noise is running, I have found that it will stop in a few hours by taking a gram of vitamin C per hour.   

Typical reference range for plasma vitamin C is 0.2 – 2 mg/dL or 11 – 114 µmol/L.  In the study, Dr. Raghavan found that oral supplementation of 5 mg of Metadichol per day raised the plasma vitamin C to or above high normal.  Speculation has been that Metadichol accomplishes this by reducing the requirement for vitamin C as the body gets healthier, recycles vitamin C, or turns on the gene responsible for producing vitamin C.  In any case, this case study shows the effectiveness of Metadichol in reducing disease.
Metadichol® Induced High Levels of Vitamin C: Case Studies
Raghavan PR* Metadichol-Induced-high VitaminC levels (link to paper)
Abstract
We recently reported that Metadichol® [1] brings about a three to four-fold increase in Vitamin C levels in patients without the use of Vitamin C supplementation. In this study of 6 patients who experienced a 5-12 fold increase in plasma Vitamin C levels higher than 80-100 u mol/L level which is the highest reported to date by oral supplementation at high doses of Vitamin C. Metadichol improved in these patients TSH levels, normalized High Blood pressure, fasting glucose levels, reduced eosinophil count, high triglycerides, body fat reduction and increased bone mass, normalized sodium levels, reducing high insulin levels, increased creatinine output in urine and also reducing of Red Cell Distribution width %. Metadichol thus serves as a surrogate for Vitamin C at doses of 5 mg per day as opposed to mega doses that are currently used.

Other articles on Metadichol

July Papers for Metadichol

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Dr. P. R. Raghavan has written two new papers for Metadichol. This again shows the diversity with which Metadichol acts.  Metadichol acts on hundreds of genes to allow the body to repair.

The first paper is about the only known substance to act for red blood cell distribution width improvement (RDW). It is believed that RDW is a marker for many types of autoimmune diseases.  Here is the summary for the paper.

 Abstract

Red blood cells originate in the bone marrow. Red cell distribution width (RDW) show sizes of circulating erythrocytes (RBC) and has been explored in several large clinical databases to be a robust marker of adverse clinical outcomes in patients. The prognostic value of RDW is seen in other conditions with end-organ dysfunction such as renal failure or. Elevated RDW levels are of significance in diseases such as kidney diseases. The high RDW levels are an indication of increased oxidative stress and closely related to the presence and poor prognosis of the disease. No known therapy exists that can normalize RDW levels. In this paper, we present here case studies using Metadichol®, that leads to normal RDW levels in patients with CKD and PKD.  Here is the link: RDW-paper

The second paper is about allowing vitamin C to be naturally produced in the body.  This is very unusual, but Dr. Raghavan believes that Metadichol activates the gene responsible for producing vitamin D.  This is based on the genes that are activated that were found in his gene studies.  Here is the summary for the paper.

Abstract

Vitamin C, also known as ascorbic acid, is a water-soluble antioxidant. Today we meet our requirements of vitamin C through consumption of fruits and vegetables or by supplementation. Homo sapiens cannot produce vitamin C like many other species that can convert glucose to vitamin C. The gene for enzyme production is dormant in humans. The gene, GULO, that we all carry converts glucose to Vitamin C. in other species but not in humans and primates. The open-label study showed Metadichol® raised levels of vitamin C by 3-fold, endogenously without supplementation of Vitamin C. Possible mechanisms for the increased Vitamin C levels through antioxidant pathways are presented. Metadichol® [1] is a nano-formulation of long chain alcohols derived from sugar cane. In addition to increased Vitamin C levels reduction in Potassium and uric acid, and decreased blood pressure and improvement in quality of life issues were also observed.  Here is the link to the paper: vitamiC-metadichol

Whatever you may think about the action of Metadichol, I believe it to be truly amazing. Here is a link for all Metadichol articles and papers.  –Pandemic Survivor

Hypertension – Reduced with A Food – Metadichol

Our diets over the last fifty years have been shifted away from fat and toward carbohydrates with the belief that higher amounts of fat were causing cardiovascular disease (CVD). As this move toward higher density carbs occurred, blood pressure also increased along with the issues of higher incidence of CVD and stroke. In the following study, a food substance, that is typically tossed in the processing of sugar cane, was found to reduce blood pressure and c-reactive protein (CRP) and increased circulating vitamin C. The paper describes the action of nano-policosanol as acting along vitamin D pathways.

Here is my blood pressure as I write this at 4 AM–not bad.Hypertension w

Dr. P.R. Raghavan has given us Metadichol, a nano-policosanol, to reduce blood pressure.  Policosanol, as long chain fatty acids, is found in high concentration on sugar cane and the husk of seeds.  Here is the paper that was just published for a sixty-week open label study. The remarkable things are that blood pressure is reduced in only three weeks, the production of vitamin C in humans, and reduced CRP, an indication of reduced inflammation.

Systolic and Diastolic BP Control in Metabolic Syndrome Patients with Metadichol® a Novel Nano Emulsion Lipid – Journal of Cardiology and Cardiovascular Therapy Case Report Volume 5 Issue 2 – May 2017 DOI: 10.19080/JOCCT.2017.05.555660 Metadichol-Hypertension

To combat high-blood pressure the normal course is to:

  • Eat a healthy diet
  • Regular exercise
  • No nicotine use as it shrinks arteries
  • Limit alcohol
  • Maintain a healthy weight

The above is the typical verbiage that you get from your doctor. I wonder just how many times the physicians say that on any given day. It is apparent that a healthy lifestyle is everything. Of course, government and its agencies have failed us in defining a healthy diet. The common American diet was defined to promote the economy. If you don’t believe this then ask yourself this question: Why do we spend almost twice as much on healthcare as we do on food?

Poor eating habits are the cause of many chronic diseases.  Hypertension falls in this category. The first time my realization that diet was critical to controlling blood pressure occurred when I was reading “Protein Power” by Drs. Michael and Mary Eades.  They warned of blood pressure dropping significantly with the reduction of carbohydrates. This raises the question of our health actions over the last fifty years. Reduce the amount of fat and increase sugar?  Sugar has typically not been considered as dangerous, however, I believe it’s the worst policy we could have made. Linus Pauling (interesting that this is the vitamin C guy and Metadichol helps the body produce vitamin C) showed in the 1970s that sugar was more responsible for increased cholesterol than fat through his studies with prisoners.

  • The real solution to maintain a normal blood pressure is to eliminate sugar and flour from your diet. Grains were not meant to be finely divided for consumption by our physiology.  Sugar is not meant to be consumed outside of its normal occurrence in vegetables and fruits. This is what is meant when we are told to consume a healthy diet.

Metadichol will help maintain a lower blood pressure. Metadichol acts in many ways in controlling our biological actions. The beauty of Metadichol is that this food substance has no known side effects. We no longer consume policosanol that is found in the husk of seeds. It appears that our body needs these long chain fatty alcohols. Metadichol is taking the husk into a modern factory and chewing them for us. Remember the words of your mother: Chew your food!  Of course, if you don’t have the right part of the food to be chewed, factory chewing by others is okay.

The irony is that nature gave us policosanol on the plants that are high in sugar, and we throw way nature’s protection from sugar.  We then concentrate the sugar through modern processes and consume it in great amounts.  Results are devastating to our health. We now develop a substance that counteracts the effects of sugar, that nature originally meant us to consumed with the plant.  Sugar drives up serum cholesterol more so than fat. The result of a high sugar diet without the protection of policosanol is CVD and stroke. More irony, the original intent of the Dr. Raghavan was to improve the way policosanol reduced cholesterol as shown by the Cubans. Nature is laughing at us.

One of the very interesting findings in this study was the increase in vitamin C. The paper indicates that humans made vitamin C as part of our physiology.  At some point, one of the three enzymes that makes vitamin C from sugar was no longer produced.  Metadichol appears to turn on the gene responsible for producing this enzyme and higher vitamin C levels happen. This means reduced inflammation, as indicated by a reduction in CRP, and the possibility of a longer lifespan with less disease.

This is really-exciting stuff. The possibility of increased life span with reduced inflammation and disease through a food substance that can easily be supplemented with no side effects–Metadichol.

We took the chewing of grains into the milling operations to help foods be easier to consume. Sugar was concentrated through industrial processes as our body craves this substance. It should also be noted that sugar was concentrated to help in the production of alcohol–another craved substance. Both things, milled grains and concentrated sugar, made food easier to consume and have significant impact on our economy, but they are not healthy. By not being healthy, we again have made a significant impact on our economy with increased healthcare and insurance. And, the government said, “It is good.”  –Pandemic Survivor