A Breakthrough in Health and Extending Life Expectancy

TelemeresMetadichol® strikes again by improving the quality of life, eliminating disease, and extending life expectancy. This plant-based substance or food has shown many ways that it acts to reduce disease and improve health in general. Now the developer, Dr. P. R. Raghavan of Nanorx, Inc., has shown that it increases telomerase or the enzyme for maintaining and increasing the length of telomeres. From the press release: Aging is a law of nature and unavoidable. Instead of targeting a multitude of diseases that confront us as we age Metadichol® is about correcting the root cause of disease.

Telomeres are proteins that are at the ends of each chromosome to prevent the chromosome from sticking to other chromosomes and to protect the genes inside by keeping the chromosome from unraveling. The best way to think about how telomeres act is to imagine the end of a shoe string. How many times have you had the plastic protector on the end of the shoe string come off, and the shoe string begin to fray and unravel? The telomeres also act, during the duplication process of RNA/DNA, as a shield to prevent mishaps.

It has been shown that there are a limited number of reproduction of cells as each time the reproduction occurs, the length of the telomeres is reduced. In other words, the length of your telomeres is an indication of life expectancy. As you age, the telomeres shorten and allow the opportunity for chronic disease, like cancer. By increasing the amount of telomerase, the enzyme that keeps telomeres healthy, Metadichol® acts to improve health and extend life.

From a recent paper: The Quest for Immortality: Introducing Metadichol®, A Novel Telomerase Activator, Journal of Stem Cell Research and Therapy.
Link to paper: Telomerase-paper

Abstract
Humans are keenly aware of their mortality. Given a limited time what we do with our life is a reflection of knowledge of our mortality. In 2009 the Nobel prize in medicine to Jack W Szostak, Elizabeth Blackburn, and Carol W Greider for their work on Telomerase and scientific research exploded in this area. Telomere protect chromosome ends and the Telomerase enzyme maintains Telomere length. This activity of Telomerase is essential in aging and stem cells and achieving longer life spans.
    Telomerase is expressed in 85% of human cancer cell lines, but its enzymatic activity is not detectable in most human somatic cells which constitute the vast majority of the cells in the human body. There is a need for increased telomerase activity in stem cells for use in the treatment of therapies where there is an active role for telomerase. Umbilical Cord Blood (UCB) provides an attractive source of stem cells for research and therapeutic uses. Work shown here characterizes the gene expression changes from Umbilical cord cells differentiate toward telomerase on treatment with Metadichol®.
     Metadichol® is a nanoemulsion of long-chain alcohols that is nontoxic. It is a mixture of long-chain alcohols derived from food. The work presented here is about the effect of Metadichol® on Telomerase expression profile in Umbilical cord cells. Our results using q-RT-PCR show increases of mRNA telomerase expression by Sixteen-fold at one picogram but down-regulates expression at higher concentrations of 100 pg, 1 ng, 100 ng and one microgram per ml concentration. Western blot studies showed expression of Telomerase protein which is slightly higher than control at one picogram, i.e., Telomerase protein expression continues at replacement level. Since it is devoid of toxic effects, it can be directly tested on humans and is in use today as an immune boosting supplement. Metadichol® increases expression of Klotho an anti-aging gene expression in cancer cell lines by Four to Ten-fold, and Klotho gene has been documented to inhibits the growth of cancer cells. Metadichol® also inhibits TNF, ICAM1, CCL2, and BCAT1 which that is associated with proliferation in yeast and increased metastatic potential in human cancers. It paves the way for safe clinical testing and research and study of Telomerase biology and its use in humans. 

The brilliance of Metadichol is that it is a food and has no known side effects—what a great nutraceutical. –by Mark Pegram

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Medicine…Money…Economics…Ethics

Health or WealthWhich of the above is more important to you? Are great economics with poor health your desire. Is it okay for the most elite scholars to avoid ethics so that they and the institution they work for have a better opportunity for wealth? We, as Americans, have paid for the research on vitamins and minerals and food (VMF). Yet, the value of VMF is hidden from us for the sake of a robust economy.

All the above are inexorably intertwined. There cannot be a large medical economy without a large sick population. Many have coined the word “sick care” for the present state of healthcare in the US. Drugs and cutting are the typical treatments for chronic disease. Disease that could be treated with VMF. If you had proper VMF before you age, then most likely, you would never reach the state of chronic disease. You would simply age and then with a few months of illness, you would pass. Please read Looking Good, Feeling Better for a better understanding.

Many researchers have not published the benefits of VMF in the hopes of being able to make an analog (prescription drug with side effects because it is not natural to the body) of the VMF for profit. We cannot point our finger at any one institution and say that they are at fault. We are all at fault. Government for allowing institutions to profit from illness while cures in VMF exist. Americans for allowing our government to get away with it in a democratic republic. In our Declaration of independence are the words— “life, liberty, and happiness.” Where is the happiness when you are in so much pain from chronic disease that life is miserable? Are you really going to turn to opiates for relief?

We hold doctors up as being the final decision makers for health. This is not the case. Let me state that again. Doctors are not responsible for the interpretation of the science of medicine. They must follow the medical guidelines as set up by the Agency for Healthcare Research and Quality. AHRQ takes its lead from the Secretary of Health and Human Services and ultimately the President and Congress. Do you think that HHS has your best interest in mind for life, liberty, and happiness? They operate by the principle of “markets before mandates” as clearly stated by Secretary Michael Leavitt in 2008. Note that to value life is the very last. The economy is more important than your health and consequently your happiness.

The archived site that stated these principles has been taken down. Here are government’s nine principles for taking care of your health:

  1. National standards, neighborhood solutions
    2.      Collaborations, not polarization
    3.      Solutions transcend political boundaries
    4.      Markets before mandates
    5.      Protect privacy
    6.      Science for facts, processes for priorities
    7.      Reward result not programs
    8.      Change a heart, change a nation
    9.      Value life

Do you need to have a robust economy for happiness? The government believes so. Is this where the institution of government is more important than the individual it serves. Isn’t this the very definition of evil? M. Scott Peck in his book, “People of the Lie,” uses the Me Li massacre in Vietnam to explain this very point. The squad was given the command that it must survive at all cost because of the importance of the mission that lay ahead. They went into a village with this understanding and proceeded to kill anyone that posed a treat including defenseless women and children.

Instead of bullets that kill you instantly, the institutions that profit use a disinformation playbook that has been around for years or least since WWII when the government sued seventeen multinationals for conspiracy for manipulation of vitamin D pricing and amounts in over the counter supplements. Dr. William B. Grant has published his version of it at Orthomolecular.org.

(OMNS Oct 1, 2018) A “Disinformation Playbook” has been used for decades by corporations to delay government action on matters of public interest that would adversely affect their income and profit. Some well-known examples include the big tobacco companies, the coal and oil industries, the sugar industry, and the National Football League. The Union of Concerned Scientists has outlined five “pillars” of the Playbook [Disinformation Playbook], [Alvord 2017]. Big Pharma may be using the Playbook to slow the adoption of strong support for vitamin D. This article is the product of my further analysis.

The Disinformation Playbook
1. The Fake
Conduct counterfeit science and try to pass it off as legitimate research.
2. The Blitz
Harass scientists who speak out with results or views inconvenient for industry.
3. The Diversion
Manufacture uncertainty about science where little or none exists.
4. The Screen
Buy credibility through alliances with academia or professional societies.
5. The Fix
Manipulate government officials or processes to influence policy inappropriately.

William B. Grant published a paper in 2009 called “In Defense of the Sun.” In the paper he shows that by just raising the level of serum vitamin D (25OHD) to 45 ng/ml, 400,000/yr. premature deaths could be stopped in the US. That is just vitamin D. What about the rest of the vitamins and minerals that we are deficient—vitamin C, magnesium, iodine, organic sulfate, zinc, vitamin B12, folate (not folic acid), and omega 3 fats. That is just the beginning of health. When is science going to admit that the placebo effect or the mind/body connection is just as powerful as most drugs that are on the market? Living longer and feeling better should be our goal. Otherwise, a strong economy is just that and cannot bring happiness because of illness. –Mark Pegram

Improved Longevity with Metadichol

Life Ext

Scientist at ETH Zurich and the Jena Hospital in Germany completed a study of over 40,000 genes and identified 30 that allowed for extended life span in worms, fish, and mice. Many of the genes extended life span by around 5%, but there was one gene that extended life by up to 25%: BCAT1.  Here’s the story.  It has long been a quest for humankind to extend life.  Here is a story of the Ponce de Leon’s of our era. There are several compounds that have been identified that impact the BACT1 gene.  A study is ongoing for the popular diabetes drug, Metformin, to extend life. To clarify, the BACT1 gene is responsible for catabolism of branched chain amino acids (BCAA).

When Metadichol (a nano version of policosanol) was compared to gabapentin and policosanol it was found to be 3000 times more effective than gabapentin in its impact on the BCAT1 gene.  Here is a link (pdf) to the paper “Improving Longevity with Metadichol by Inhibiting the BCAT1 Gene” for download Metadichol-BCAT1-paper .

It seems that the truth of extending life lies in the idea of having the least number of illnesses during your life.  I wrote an article about this some six years prior:  Filling Good, Looking Better.  In my reading, I think I came across this idea from Linus Pauling during the 70s in his book, “How to Live Longer and Feel Better.” Ideally, it is not just about extending life, the best solution is to have a healthy, vibrant life. Pauling promoted many ideas about how to be healthy (and by-the-way won two Nobel Prizes).  His largest push that he is remembered for is vitamin C.  His promotion of vitamin C has now been supported by modern research. However, he also promoted healthy eating and the reduction of sugar consumption, now a very modern idea.  He even did a study on prisoners to show that it was sugar and not fat that drove up cholesterol.  Long life by reducing disease appears to be the case for BCAAs as they impact your health on many levels.

The idea of extending life by reducing disease gets exciting when considering Metadichol. It appears to reduce disease on many different levels that just happen to include the metabolism of BCAA. Here are the many articles that I have written about Metadichol.  The beauty of Metadichol is that it is a food substance and not a drug and has no known side effects.

The idea is not to just extend your life span, it is to have a happy, healthy, and vibrant life.  To accomplish this: It is about understanding your emotions and living in flow; it is about eating a healthy diet that eliminates flour, sugar, and other processed foods; it is about getting adequate amounts of vitamins and minerals that are much higher than the RDAs of our government; it is about eliminating environmental toxins like nicotine, mercury, and the salt substitute MSG; and it is about eliminating the side effects from prescription drugs (In other words, stay healthy and don’t take prescription drugs).  To your healthy life that will allow you to live to 120 years old. –Pandemic Survivor 

The State of Health in the US

SMMIt has become apparent to me over the last several decades that manipulation of health and life expectancy for economic purposes is real. I have thought for most of the last ten years that it was just incompetence on the part of doctors, failure by our government to properly manage their role, and lack of education on the part of the populace. Yes it is still some of all of these combined, however, it has become apparent that there is a real conspiracy happening. It is being carried out simply for the gain of politicians and their ilk as lifelong employees of government who believe by controlling your life; they are giving you a better America. We come together as a people to form government to help protect the interests of the population as a whole, not for the few. If government believes they are presently protecting it for the many, then we have a serious problem on our hands as thousands suffer needlessly and die at the wish of our politicians.

We live in the greatest country in the world and I love America. I am not discussing here the heart-felt efforts of the many physicians who have worked sacrificially to save lives from many forms of disease or the tireless work of researchers to develop treatments. I am speaking primarily to the people at the top of decision making of our institutions who have intentionally allowed death and suffering through their policies. Health and Human Services was even brave enough to state this policy as part of their nine principles of operation in the 2000s. Of the nine principles, markets before mandates, was number four, and to value life was number nine, the last.

Politicians and large institutions, (health insurers are the worst of the worst as they profit from your suffering and the more you suffer the better their sales, and only fifty cents of every dollar you give them comes back as payment to providers–but, believe the politicians, that they are growing our economy through manipulation of health insurance) are using the complexity of life and medicine to simply manipulate outcomes. The main tool of this obfuscation is to promote the use of patent medicine over the use of nutrition to allow the body to heal. Patent medicines are used simply to treat symptoms with the hope that the body will heal on its own. The only real exceptions to this are antibiotics and some vaccines. But now, even the vaccine market is being manipulated for higher sales. We use screening to find cancer earlier in its state of development and chemo and cutting for treatment to make the claim that we are giving increased life when our death rate from cancer has not declined at all. It is plain to see that the ones benefitting from this misdirection are not the patients and the payers of expensive research and treatments — you. Of course, if you are receiving income from the health sector, as one in five of every American, then you too are benefitting from this treachery.

The importance of economics over life started in the nineteenth century and became magnified in the twentieth century as patent medicines were held up as more important than nutrition for healing. This is certainly true for emergency medicine, but very damaging for treating chronic disease and the hope of a long life. Now, you will see many ads state that nutrients are not for treatment, diagnosis, or cure of any disease to stay within the confines of our politician’s laws. I suspect if medical practice was changed to use patent medicine for emergencies and nutrition for chronic disease, life expectancy would increase to over ninety years old. A good life to a ripe old age, your period of suffering would be very brief.

If a visit to the doctor for a chronic concern started with tests and diagnosis evolved around which nutrients your were most deficient, there would not be the need of almost any patent medicines. “Well let’s see Mr. Patient, it looks like you are not getting enough protein and balance of protein and fats so that you will heal. Also, you need more greens for folate to help generate stem cells and you need to spend more time in the sun for vitamin D. Also I have found several mineral deficiencies which can be corrected by changing your eating habits to allow for more variety. If you don’t want to change your eating habits, then I can simply write you a script for this combination of vitamins and minerals based on my testing to improve your health.” Sound weird? It is only because your mindset has been manipulated toward patent drugs.

The state of medicine, interwoven with economics, is now so complex and complicated; it will take an extreme effort to make the change.   Currently the most egregious actions are the hiding of research outcomes for vaccines that increase the rate of autism (the CDC admitted to this over eighteen months ago) and the serious error that was made for vitamin D RDI by the National Academy of Medicine (formerly the Institute of Medicine) in 2010. Just these two things are causing significant suffering, causing thousands of deaths each day, and significantly impacting healthcare cost. And yet, no action has been taken. The press is conflicted over the loss of revenue if they report on the errors. What are you going to do about? – Pandemic Survivor

Amazing Media Reports or Popular Press Propaganda

This Labor Day weekend, I was alarmed by the media reports about life extension and supplements and a new drug development. First the new drug development that startled me as it sounded a lot like a vitamin D analog.

I was watching Fox News on Monday morning. Yes I know, if you have a liberal political persuasion you have already labeled me and not consider reading further. There was an interview with a doctor about a new drug that would significantly reduce heart disease and also significantly reduce all-cause mortality. It will likely be approved by the end of the year. This sounds a very fast track. A very fast track is a good thing if there are no side effects, a low number needed to treat, NNT, and we can put an end to heart disease. The drug had not been named which was another surprise to me. What really got me going was the description of how it acted. Here is the print article from Fox News.

It was not only reported to reduce heart disease, it was also stated that it would significantly increase life expectancy. Why was I alarmed? It sounded like vitamin D3. First there was the interview with a Dr. Joseph Prendergast from about 2007 where he reported that he had been extremely successful in treating heart disease with vitamin D3 and L-arginine. He said in the interview that he had been so successful that a three physician cardiology practice in the same town that he practice had moved to another town because of lack of business. He had treated more than four thousand patients. Then there is the description by Dr. William Davis, a cardiologist and author of the book “Wheat Belly”, that claims in his practice there are not anymore emergency calls from his patients. He says that he used a variety of nutrients with Vitamin D being a very important one. And then I remembered all the published papers on how vitamin D3 significantly reduces heart disease collected by Henry Lahore at VitaminDWiki.    Cardiovascular Disease  Also the many articles at the Vitamin D Council related to cardiovascular disease and vitamin D3.  And on and on.

What is more alarming is the NNT, before a positive outcome, the prevention of death. “About 32 people would need to be treated with the new drug to prevent one death from heart-related causes. “ This description does not sound as if the drug is effective as just plain vitamin D3 that can be purchased over the counter. This sounds significantly different that the experience of Dr. Prendergast and Dr. Davis and the multiple of medical papers published on the subject.   As a society, are we so set in maintaining the medical economy that doctors cannot tell people that vitamin D is very significant in the course of heart disease? When other specific nutrients are added and changes in diet, heart disease could be a thing of the past.

The second report was on CBS 60 Minutes. They had a segment on research with the aging of what extended life and what did not. It was very educational and interesting until Leslie Stahl asked about supplements. The answer was no, there was not any significant reduction of death with supplements. She then asked a much scripted question. No help from vitamin E? No. No help with vitamin A, vitamin B, and vitamin C. No. No help with a multiple vitamin? No. Notice the order of vitamins not to take the listener to vitamin D as they were not in alphabetical order. Also note that the question was not asked about vitamin D. There was a bottle of vitamin D3 plainly on display in the cabinet. Plainly getting the viewer to believe that vitamin D3 has no affect without stating. Subliminal communication at its best! There are papers stating that life expectancy could be extended by seven or more years with higher levels of vitamin D3? Mortality and Vitamin D3

Propaganda delivered at its very best! – Pandemic Survivor

Supplements are useless if you want to die!

Don’t take vitamins and minerals as they are a waste of time and money. You get enough nutrients through the food that you eat. This is repeated over and over again by the powers that control our health. Food is much more important to your health than medicine and yet we spend almost 77% more on health than we do on food (1.264 trillion for food and 2.237 trillion for healthcare). When you are trying to determine the purpose and paths that are placed on us, often the statement, “follow the money,” arises.

We find that we are last in the twenty wealthiest countries of the world in life expectancy and spend much more than any other country on health. If the numbers for spending on healthcare and food were reversed, then we might have a chance for a much longer life expectancy.

I am often asked what I take to prevent illness. When I tell them, there is much concern about taking so many tablets. In the mind of the average American is the issue that this many ‘pills’ could have very serious side effects and might make them sick. This is what has been perpetrated on the American public. Vitamins and minerals are not good for you and like pharmaceuticals should be pharmaceuticals are not good for you like vitamins and minerals. However, vitamins and minerals do not have serious side effects like pharmaceuticals. But if it is in the form of a pharmaceutical then we make assumptions that are not correct about the side effects. Please note that I have said vitamins and minerals. When you start to take herbs then this is no different than taking a pharmaceutical. Most pharmaceuticals have some basis in herbal origins.

The issue is how we process foods and change the characteristics of the nutrients. In many cases nutrients are not only changed, they are completely stripped from the food through processing. The major forms of processes that destroy food are over-heating and mechanical shear like homogenization and size reduction. A change in the characteristics of enzymes, protein, and fat affects the ability of the body to absorb the proper nutrients. We have now arrived at the point that we must take supplements in addition to the food that we eat to be healthy. Of course this says nothing about the synthetic vitamins that are put into our foods or pesticide and herbicide toxins affect on health.

Here are the additional nutrients I take on a daily basis. Compliance by most in taking the additional nutrients is difficult because it is not a fast food burger or a bowel of ice cream. Also, the form looks like pharmaceuticals and we fear side effects.

daily1This looks like pharmaceuticals when in fact; it is just food that has to be made up from our loss in modern processes. Nutrient deficiency is the number one cause of poor health and reduced life expectancy in the US. There are not any harmful side effects. There is only health from food. For the powers to tell you otherwise is about the money made from your poor health. – Pandemic Survivor