Higher Vitamin D Intake Drastically Reduces Disease

A new study of serum levels of vitamin D shows that 4000 to 8000 IU per day are required to keep your serum level in a range that will reduce the incidence of disease. This includes cancer, type 1 diabetes, and multiple sclerosis.  Dr. Cedric Garland says that the incidence of many diseases could be reduced by half.

Here is the news article in Business Week: “Higher Vitamin D Level Could Cut Cancer Risk”

As I have described in many post, the amount of vitamin D required is different for each individual.  The only way to know that you are getting enough is to have your serum 25(OH)D level tested.  Serum levels should be maintained above 40 ng/ml, and for best results the level should be maintained between 60 to 80 ng/ml year round.  You should only supplement with Vitamin D3.

For a better understanding of the science, here is the journal article that was published in Anticancer Research, International Journal of Cancer Research and Treatment, made available in its entirety by Grass Roots Health.

Vitamin D Supplement Doses and Serum 25-Hydroxyvitamin D in the Range Associated with Cancer Prevention

CEDRIC F. GARLAND, CHRISTINE B. FRENCH, , LEO L. BAGGERLY, and ROBERT P. HEANEY (here is the url in case you cannot go there from the above link  http://www.grassrootshealth.net/garland02-11)

“This paper provides a long awaited insight into a dose-response relationship between orally administered vitamin D3 and the resulting levels of serum 25(OH)D in over 3600 citizens. The results will allow new definition of high vitamin D dose safety and reduce concerns about toxicity. This is a landmark contribution in the vitamin D nutrition field!”

Pandemic Survivor

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Sunday Morning Musings

So what is going on with influenza like illness?  We have seen a significant drop in the rate after a spike in September and October.  We are now at rates that are very similar to last year in late January.  Given that we see a 33% Fibonacci return in this chaotic statistic, the knee will mirror 2009 February and March results or just another normal flu season. Graph at this link.

There has been much chatter about the efficaciousness of the H1N1 vaccine.  The EU in particular is taking on the large pharmaceuticals over this issue.  I believe that the H1N1 is a none-mutating virus to date and has effectively played havoc with people that were susceptible.  The reason that the spike occurred in September and October instead of later is because this is the first drop in serum levels of vitamin D in the northern latitudes.  A similar type of occurrence happened in the southern hemisphere in our summer which makes me wonder at the push by our government over the vaccine.  We have been much more effective is getting the message out about vitamin D.  If the spike in February is not similar to last year and also make a Fibonacci return then people in the US have blunted the virus by taking vitamin D.  I know that this is a very technical mathematical predication, but if you deal with stocks or currency trading, you know this analysis is correct.  The technical changes are very predictable in chaotic markets as long as there is not a fundamental change like an economic news such as an increase in the number of lost jobs.  In our case the fundamental change is increased use of vitamin D.

I have been keeping up with people that I have casual conversations about vitamin D and whether their doctor has ask to check their serum 25(OH)D levels.  I am happy to say that approximately 1 out of 6 of the people that I have talked with has had their serum level checked.  This is up from zero 5 years ago.  Dr. John Cannell of the Vitamin D Council goal is to have every one’s serum vitamin D routinely check by their physician.  John, I believe that we are starting to reach a tipping point.   However, even at this low rate we could see as much as a 5% drop in the rate of total cancer in the US over the next two years.  I know that this is a bold prediction but the research is there.  If the Food and Nutrition Board on vitamin D comes out with a favorable report in May saying that everyone should take more, the amount of reduction in cancer will amaze you as well as heart disease and diabetes in more time as these diseases take longer to respond.  The manufacturers of cold remedies will start to feel the pinch as people start to use significantly less.  They will simply create other products to fill the voids.

Interesting article at Boots WebMD saying that increased levels of vitamin D could reduce the incidence of colorectal cancer by 40%.  I do not know what the big deal is.  In November of 2007 the National Cancer Institute came out with a report as a rebuttal to the Lappe finding at Creighton University.  The Lappe finding showed a 60% ( or 77% when taking out the tumors not found in the initial screening that occurred in the first year of the trial) reduction in total cancer in a placebo control double blind study.  NCI did an epidemiological study based on flawed data (questionable and two few actual test data on serum levels of vitamin D) and even then as you read through the abstract it said something to the effect that there was no relationship between higher vitamin D levels and cancer except that there was a 75% reduction in death from colorectal cancer in the higher quintals of vitamin D.  Well dang NCI isn’t this enough to trigger treatment trials with people with cancer and not just prevention trials.  Maybe they are not just ignoring the facts but acting with disdain.  Given these numbers you can see why I think that just a modest improvement in supplementation and (trips to the Caribbean or Hawaii in the winter for you rich people) will have significant impact on cancer.

You know one of the things that I have notice when talking with people is the lack of consistency in taking vitamin D.  They typically take two small an amount when supplementing or they just skip days while taking this small amount.  Remember the serum half life of vitamin D at 30 ng/ml is approximately three weeks.  This means that after three weeks with no supplementation or exposure to tanning that your serum level is 15 ng/ml.  At higher rates this half life is much reduce.  I need to do more reading on this, but I found one study that said that the half life at 100 ng/ml was only 5 days.  This seems like two short amount of time but if it is correct then compliance when supplementing is extremely critical.  This also explains why people at latitudes close to the equator catch viruses more easily in the rainy season when there is not much sun.

Ah, for a two week repose on the garden island of Kauai that would drive away the winter blues and chronic disease.  Maybe I can make that happen if I were president.  I would certainly declare a national emergency for vitamin D deficiency.  Living easy with the sun in my mind and vitamin D supplements at hand –  Pandemic Survivor

Vitamin D, Disease, and Research

In 2006, I went to PubMed, the government clearing house for medical publications, and just entered vitamin D in the search engine and limited the search to that year.  There were over 2,100 papers.  I just did this for 2008 and there were over 2,300 papers.  If you limit it to the last ten years it comes up with over 17,000 papers.  The published recent work on vitamin D is voluminous.

The Vitamin D Council has provided a wonderful list of diseases that have been associated with vitamin D deficiency on their research page.  You go there, pick the disease and it sends you to PubMed right to the abstract of the article.  If you do not have a subscription to the particular journal you can purchase the article from the publisher online.

In reading this list, it makes me wonder why there are so many diseases and so much research and yet the medical profession is not treating with vitamin D.  There are so many diseases that are a result of or have a component related to D deficiency, you would think the news organizations would be all over this, but I digress.

If you are a doctor or a researcher and you are trying to just get a feel for the research that is out there then Dr. John Cannell has organized the research by disease.  It is a starting place as there are still many diseases that he has not listed.  For example, I had degenerative disc disease that is really a form of osteoarthritis.  This disease caused severe chronic pain, muscle wasting in my legs, central sleep apnea, memory loss from brain shrinkage with the pain, and other symptoms from oxygen deprivation from the sleep apnea.  If we took sleep apnea we find that it is not in the list because no one has done any research on it and vitamin D even though it has an obesity and stenosis vector which both can be tied directly to vitamin D deficiency.  There is a lot of work that is left to be done and a lot of miss-education of doctors, researchers, and the public in general that needs to be corrected.

Another disease that is not listed is psoriasis and I know that it can be treated with vitamin D according to Dr. Michael Holick of Boston University.  Dr. John Cannell has done a great job and we are grateful for his work, but the tentacles of vitamin D reach far and long in the course of human health and disease.

If you do not find the disease that you have interest with, then just go to PubMed and search on the disease itself and components of vitamin D.  Also I am sure that if you can identify research and that has not been listed then the Vitamin D Council would be interested.  Send that along to them.

Let’s just make a copy of the list without comment to see how long it is:

Vitamin D Council Research Links by Disease

Addison’s Disease
Allergic Hypersensitivity
Alzheimer’s Disease
Ankylosing Spondylitis
Asthma
Autism
Autoimmune Illness
Benign Prostatic Hyperplasia
Bladder Cancer
Brain Cancer
Breast Cancer
Cancer
Celiac Disease
Cerebral Palsy
Chronic Obstructive Pulmonary Disease (COPD)
Chronic Pain
Cognitive Function
Colon and Rectal Cancer
Cystic Fibrosis
Depression and Seasonal Affective Disorder
Diabetes
Endometrial Cancer
Epilepsy
Ethnicity and Vitamin D
Eye Cancer
GastrointestinalFunction
Gaucher’s and Fabry’s Disease
Vitamin D and Genetics
Graves’ Disease
Hashimoto’s Thyroiditis
Heart Disease
HIV and AIDS
Hypertension
Inflammatory Bowel Disease
Influenza
Innate and Adaptive Immunity
Liver Cancer
Liver Function
Lung Cancer
Lymphoid Cancer
Melanoma
Mental Illness
Mineral Metabolism
Multiple Sclerosis
Muscular Weakness and Falls
Obesity
Osteoarthritis
Osteomalacia
Osteopenia
Ovarian Cancer
Pancreatic Cancer
Parathyroid Function
Parkinson’s Disease
Pediatrics
Post menopause
Pregnancy and Lactation
Premenstrual Syndrome
Prostate Cancer
Renal Function
Rickets
Sarcoidosis
Sickle Cell Disease
Skin Cancer
Stroke
Toxicity
Toxin and Radiation Exposure
Tuberculosis
Turner’s Syndrome
Vitamin D Deficiency

Other items of interest for Vitamin D with links to the research:
Best Science
Commentaries and Editorials
Genetics
Requirements
Reviews
Treatment
UV Exposure
Veterinary and Animal Studies
Worst Studies

Vitamin D Council Research Links by Disease

Well, I hope that you find this useful and that you do not think that just because your disease of interest is not in this list that it does not have a vitamin D vector.  This seccosteroid is the most important steroid of the human body – Vitamin D3.

There is a lot of pain and death listed above.  Shine the light on this research!!!  – Pandemic Survivor

Blast Your Concerns about Cancer Away with Dynamite (DINOMIT)

Dr. Cedric Garland has been researching cancer and vitamin D for over thirty years.  Through Grass Roots Health and University of California San Diego, he has released a video talking about the stages of cancer and how vitamin D and calcium acts at many stages.

Until now typical treatment and prevention only considers Initiation, Overgrowth, and Metastasis.  He describes the additional stages as follows:

D – Disjunction

I – Initiation (genetic variation)

N – Natural selection

O – Overgrowth

M – Metastasis

I – Involution (cancer stops or slows)

T – Cancer becomes chronic condition)

A must watch video for doctors, researchers, oncologist, those concerned about cancer and cancer patients.  This University of California San Diego – TV video:  How Vitamin D Reduces the Incidence of Cancer: The DINOMIT Model by Dr. Cedric Garland.  For best results Dr. Garland says that you should get your serum 25(OH)D above 60 ng/ml.  Everyones serum level responds differently depending on disease state and body mass.  You most likely will need between 4000 IU to 10,000 IU per day of D3 from all sources.  The only way that you know for sure that your serum level is maintained is to have a blood test.

I would not suggest that you use D2 because it does seem to act the same as D3.  D2 and D3 has always been thought by the medical profession to be equivalent but new research shows this is not the case.  D2 also seems to be more toxic.  The Vitamin D Council on Treatment with D3. and  D2 versus D3 in this paper by Armas, Hollis, Heaney.

For doctors with your concerns about toxicity:  The NIH data shows serum 25(OH)D to be safe at levels consistently below 200 ng/ml.  Animal studies have shown that levels below 400 ng/ml do not cause toxicity.  See Table 1 at the NIH Fact Sheet on Vitamin D.

Also be sure your diet has enough calcium or about 4.5 mg per pound of body weight per day as discussed in this fact sheet on calcium from the NIH.

Other presentations from Grass Roots Health and UCSD-tv.  Vitamin D Presentations

If you have cancer be sure that your oncologist sees this information and do it conjunction with whatever protocols that he recommends.

You may also want to consider watching this one hour free video from Dr. Mercola on Vitamin D to help clear up the confusion of this strategic prehormone for health.

Cancer is not necessarily a death sentance.  Take control and be healthy.

GET HEALTHY!  and my  prayers are with you. – Pandemic Survivor