Author Archives: Mark Pegram

Understanding out of Chaos

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Many Causes, One Disease, Many Cures
Resolving Multiple Factors for Disease States

“Double, double toil and trouble
Fire burn, and cauldron bubble” Hamlet, Shakespeare

Okay, this post is not for the layman in trying to resolve issues of their personal health. This post is to point researchers to a tool long used in the military and manufacturing for troubleshooting problems. The issues are multiple factor diseases. When there is more than one factor, analysis of the variance, ANOVA, only tells you that there is a statistical significance of one of the factor variances. It does not tell you which factor is causing the variance.

One of the issues that have long plagued medicine is multiple factors. In the ‘gold standard’ for statistical analysis of a drug or nutrient in how it affects a disease, typically only one factor is used. The double blind, placebo controlled trial is run. The reason for this is the complexity of the math when there is more than one factor and the understanding by decision makers of what the math model is telling you.

Elis R. Ott developed a technique for measuring multiple factors in how they vary from the average. In other words, the technique measures the group average variation from the average of the entire population. This technique is called analysis of the means. So in comparing to ANOVA it may be stated as: ANOM compares the group mean to the overall mean, where ANOVA compares the group mean to the other group means. ANOVA can tell you if there is a significant difference, while ANOM can tell which group mean is significantly different.

I can tell you from personal experience that ANOM is a very powerful statistical method to sort out both common causes and assignable causes. I was once the engineering manager for the world’s largest automotive battery plant. We made sixteen thousand batteries per day. That is over a million electrode plates per day. We of course used all the standard statistical techniques. Until ANOM was introduced, confusion continued to hold sway because the employees as well as the managers did not understand the math. When the graphical method of ANOM with the ability to compare multiple factors was introduced, we quickly achieved much higher production levels of quality product. It was also great because ANOM could be applied to either attribute data, go/no go, as well as variables data.  Also, much smaller sample sizes were needed to show significance. Clear decision making with expected results became trusted.

Here is an explanation from the SAS software statistical module: “A health care system administrator might ask which clinics in the system have a higher or lower rate of admissions than the average for all clinics. Questions of this type can be answered with analysis of means, which is an alternative to one-way analysis of variance (ANOVA) for a fixed effects model. However, unlike ANOVA, which simply determines whether there is a statistically significant difference in the treatment means, ANOM identifies the means that are significantly different. As a statistical technique, ANOM is a method for making multiple comparisons that is sometimes referred to as a “multiple comparison with the weighted mean”. Analysis of means lends itself to quality improvement applications because it has a simple graphical representation that is similar to a Shewhart chart and requires little training to interpret. This representation is also useful for assessing practical significance.”

History: “Analysis of means compares the absolute deviations of group means from their over-all mean, an approach that was initially studied by Laplace in 1827. Halperin and others derived a version of this method in the form of a multiple significance test in 1955. Ott developed a graphical representation for the test and introduced the term “analysis of means” in 1967. Refer to Ott (1967) and Ott (1975). In the 1980’s Schilling extended the application to non-normal distributions. P. R. Nelson (1982a) and L. S. Nelson (1983) provided exact critical values for ANOM when the groups have equal sample sizes. P. R. Nelson (1991) developed a method for computing exact critical values for ANOM when the group sample sizes are not equal.”

This is really great because this technique can be applied to existing data when there are multiple factors to readily point to which is the most statistically significant. You can easily decide if calcium or vitamin D is more important or better you could compare vitamin D, vitamin A, calcium, and magnesium. The thing that adds to the value of ANOM is the ability to compare the interactions of the factors. Many of the interactions will mean nothing. However, the interactions of some of the factors will be greater than any one factor. So you might find that vitamin D is great for moving the population toward health. The interaction of vitamin D and magnesium would be even greater. We can make suppositions based on our understanding of the mechanisms, but until the interactions are statistically verified it continues to be viewed as a witch’s brew.

An example of this in the nutritional community is the argument between Dr. Cannell of the Vitamin D Council and the folks over at the Weston A. Price Foundation. Dr. Cannell has held that high levels of preformed vitamin A will lead to illness because of the apparent reduction in the serum levels of vitamin D. Weston A. Price Foundation has long held the importance of vitamin A and especially cod liver oil as an elixir for health. So the question becomes is vitamin A and vitamin D antagonist or are they cofactors of each other. I personally suspect that large amount of vitamin A with small amount of vitamin D is the issue driving the assumption that large intakes of vitamin A is bad. Given two to three months for the liver to clear of stored vitamin A with a serum level of vitamin D above 60 ng/ml; I suspect health would be improved with high intakes of both vitamins. I also suspect that there is enough data currently existing in clinical trials to ferret out the answer using ANOM. One of the major advantages of ANOM is that it gives a graphical solution that is easily understood by clinicians and decision makers without having to have a complete understanding of the math operating in the background.

So the group averages of different levels of vitamin A and vitamin D may look something like this when compared to the total population.
ANOM IllstrationAfter applying ANOM you would get a graphical solution like this. This created hypothetical  example shows that both high A and high D are statically significant. But better, it shows that the interaction of vitamin A and vitamin D is even more significant. (this would make sense as the known mechanisms for growth factors, necrosis factors, and immune system improvement require VDR/RXR dimers)
ANOM DecisionIf the above ANOM is truly represented as fact, then after giving the population high amounts of vitamin A and vitamin D you would get a shift like this:

Improved wellness after applying the new understanding.

Improved wellness after applying the new understanding.

Now just imagine the power of this when analyzing a population when the levels of vitamin A, vitamin D, magnesium, and calcium are known. You would be able to see the effect of the main factors as well as the interactions of the factors and decide based on statistical significance. Or better, you could make an analysis of different levels vitamin D3, vitamin D2, vitamin A from fish liver oil, beta-carotene, magnesium oxide, magnesium chelate, calcium hydroxide, and calcium citrate all in the same study. There would be no control population required as the group averages would be compared to the average of the entire population. This is more real world than how it is done now. Also, because the interactions are so difficult to predict by individuals during the trial, the placebo effect would not be as large a factor.
The clamor over the last many years have been that vitamin D provides no consistent benefit based on meta-analyses of many studies. The beauty of using ANOM for the meta-analyses would show that dose dependence is of extreme importance. No longer would critics be able to say that vitamin D has no effect. It would be plain there are no effects at lower levels or the effects would be shown to be dose dependent for different diseases.

Imagine doing drug studies and show variations of other drugs and nutrients and interactions in the same trials with a graphical method that could be easily understood. Or imagine analyzing all of the environmental factors that are issues for a disease like autism from existing data. For this reason, the inability to show clearly which factor is most important; it is not likely that this technique will ever be adopted. I know this is a very critical statement, but it is obvious that the preference of the medical community is to keep the argument going instead of solving the problems because of the economics involved. With increased wellness in the general population, healthcare/healthcare insurance job opportunities would be significantly reduced. Our leaders have to decide which is more important, your health or the economy. I suggest that empathy for each person’s wellness would strengthen the economy to a much greater extent than creating and maintaining jobs in the healthcare sector only. It would certainly give more trust in our leadership. – Pandemic Survivor

“Think, and then plot the data.” Elis R. Ott

Further Reading: Process Quality Control: Troubleshooting and Interpretation of Data, Fourth Edition Ott, Schilling, Neubauer 2005 http://asq.org/quality-press/display-item/?item=H1222 or Amazon
The Analysis of Means: A Graphical Method for Comparing Means, Rates, and Proportions, Nelson, Wludyka, Copeland; 2005 Amazon

Many Diseases, One Cause, One Cure –The Sun

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“Fillet of a fenny snake,
In the cauldron boil and bake.
Eye of newt and toe of frog,
Wool of bat and tongue of dog,
Adder’s fork and blind-worm’s sting,
Lizard’s leg and owlet’s wing,
For a charm of powerful trouble,
Like a hell-broth boil and bubble.”
Macbeth, Shakespeare

Does this sound like your typical medical researcher toiling away at work in the laboratory? It may as well be as far as the average person is concerned. When scientists start talking about chemical and biological mechanisms or how a particular drug affects disease, I am sure this is what it sounds like. This is really unfair to the researchers for it is the spin of medical marketing that cause our heads to ‘explode’ with too much misunderstood information. Hypocrisy and deception was of course the major theme in Shakespeare’s play, Macbeth.

It is fact that the medical establishment wishes you to view holistic medicine in this manner, a witch’s brew. How many news articles have you seen in the popular press since this past December have been placed simply to discredit the use of vitamin and mineral supplements? In particular vitamin D; it is the steroid/vitamin that results from our exposure to the sun. This is the thing that is the most alarming to the medical profession. That one source can heal, treat, cure, prevent, and diagnose a disease without it being called a drug that can be exploited economically.

And just how far has the medical establishment taken the bashing of supplements and food to treat disease? They have gone as far as passing a law that says nothing but drugs can be used for purposes of healing, treating, curing, and preventing disease. I find this extremely amazing as this one law totally ties the hands of doctors in their toolbox of treatment. It was however agreed to because the other option was to allow the FDA to treat everything as a drug. This would take away our freedom of access. Dr. X, would you please write me a script for turnip greens…..

Let’s take the sun as the one thing that is responsible for many diseases if it is taken away. Without the sun, the water cycle and clean fresh air would not exist. There would be no food sources as photosynthesis would end. You would only have fungi to stay alive. If you completely took it away and everything that it gives us, you would be dead in a very short period of time. So let’s take away some degree of the sun and see what happens. You get a host of chronic disease that is used by the medical establishment and government to support a large economic sector.

This is exactly what happened in the 1960’s as a prominent pediatrician, Dr. Cook, friend of the Kennedy’s, made the public declaration that vitamin D would cause birth defects. People were scared out of the sun, especially pregnant women. The use of cod liver oil as a supplement was held in an extremely negative view by medicine. Where was the science in this art? Then there was the large campaign by the medical professionals to keep us out of the sun because we might get skin cancer. RUN, IN FEAR of cancer! Of course, there is now an extremely close correlation between the use of sunscreen and the incident of melanoma. Also, other cancers have either staid the same as far as mortality or increased even with all of our efforts in the hundreds of billions of dollars spent on cancer research. There are now at least a hundred diseases that can be traced to the lack of vitamin D or our connection to the sun. Dr. X, would please write me a script for the sun………

Do you have someone in your family or a friend that makes their income from the medical/medical insurance industry? An entrenched “protection racket” used for apparent safety that under any other circumstance would be aggressively prosecuted. “Double, double toil and trouble, Fire burns, cauldron bubbles.” – Pandemic Survivor

One Disease, One Cause, One Cure

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“Double, double toil and trouble,
Fire burn, and cauldron bubble.” – Macbeth, Shakespeare

As I have read about diseases and medical cures, I have been fascinated by the approach to problem solving. I know that these are words you don’t normally hear in medical practice – ‘problem solving.’ It is typically about the disease, the cause, and the cure. It is also amazing to me to read research papers that will end with the statement about more needed research. I always ask the question; more research about what? Biological mechanisms for creating a new drug or the multiple factors that are the cause and cure of a disease?

Typically medicine has tried to identify a specific cause of malady with a specific cure. This makes it nice and neat for both patient and doctor. However, I do now believe after reading for several decades that there is no disease that has a single factor as a cause. The only exception to this is acute disease like infections or a broken leg. If the disease is chronic in nature or occurs over time, then multiple factors always come into play. Could it be possible that an acute disease has multiple factors? I do believe this the case with the common cold and other mild infections and perhaps that broken leg as well. This may also extend to significant infections where ninety percent of the victims die like the Ebola virus. The reason that I can say this is that ten percent of the infected lived, which means that other factors have come into play other than the Ebola virus. Has anyone really asked what these factors are? Could it just be that the survivors have better nutrition with stronger immune systems? What are the nutrients that have contributed to the better immune systems?

The claim in the last hundred years is that medicine has transformed into a science instead of an art. This is a flat out fabrication. Science has come into play in a limited fashion. Science has not been applied to medicine the way it has to say manufacturing or space travel. In both of these endeavors, all factors of significant importance are always considered. Unlike medicine, there are no laws preventing problem solving of significant factors. In medicine, the most significant factors of nutrition cannot be used to treat, cure, diagnose, or prevent a disease. I find this most fascinating in the limiting or hand tying of our doctors and researchers. Of course there are some limitations of factors in manufacturing like environmental laws to protect future generations. What is being protected in medicine by limiting significant nutritional factors? I was startled at California’s attempt to make it a felony for a doctor to use nutrition to treat a disease. I guess the answer is to follow the money without empathy for the ill and dying.

Also medicine has not used all of the tools that are available to them. A great example of this is the statistical methods that are used for problem solving or troubleshooting an illness. Techniques of identifying multiple factor statistical probabilistic predications were developed for the military in the 1950’s. The techniques were them applied to manufacturing in the 1960’s. The techniques then matured in the 1970’s and 80’s. For example, are there control charts in hospitals tracking cases of MRSA to be sure that prevention methods have remained stable in hospital operations?

If it is not one disease, one cause, and one cure it seems that the solutions are too difficult to communicated to all of the decision makers. Decision makers in medicine are you the patient, the doctor, the institutional managers, the medical education community, the medical research community, the insurance institutions, and government institutions. This much complexity, prevents the swift solutions for common causes and special causes or assignable causes of illness. I am sure that W. Edward Deming and Walter A. Shewart are ‘rolling in the grave.’ The last couple of decades have seen the development of chaos theory. How long before this new science is applied to medicine with its repetitive predicative perception of nature? Or, will chaos as an artistic pursuit in medical decision making continue? – Pandemic Survivor

FDA’s New Supplement Label Rules

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It is amazing to me that the FDA can routinely decide that it will change the daily amount of vitamins and minerals and how they are described with just a wave of the hand. With their new rules on labeling, they have effectively changed the amounts of vitamins and minerals that are suggested as needed for health. Of course these numbers did not mean much anyway because they are typically stated as what is required for an average weight person to prevent certain diseases while ignoring other possibility of disease. However, it is very confusing to the average consumer as well as me and I suspect the FDA. Proposed labeling changes:

Vitamins and Minerals of concern as reported by the Alliance for Natural Health are:

Vitamin B9 or folate: The FDA wants to stop the use of folate and only allow folic acid. Folic acid is a manmade molecule that was manufactured in the laboratory in the mid 1940’s. Folate is very significant in how the methylation cycle occurs. Methylation has been shown to be responsible for how your blueprint of DNA is read and new proteins duplicated. Diseases that are impacted are everything from neural tube defects, oxygen carrying capacity of the blood, mental disorders, and arthritis to colon, breast, and prostate cancer.

Vitamin A: The FDA’s suggested change is from IU to milligrams of RAE or retinol activity equivalents. This is suggesting that beta carotene is equivalent to all the other isomers of vitamin A and ignoring the value of the pro-vitamin A and other carotenoids. Depending an individual’s enzyme profile, not all beta carotene is converted equally. It also depends on whether the beta carotene is delivered as a supplement or from natural sources.

Vitamin E: Only alpha tocopherol is recognized as the active form totally ignoring the other seven isomers of vitamin E with gamma and delta being the most important. They also ignore the value of tocotrienols for neurodegenerative disease.

Changing the DV’s or daily value has impacted the following vitamins and minerals: Reducing the amounts: Vitamin B12, zinc, vitamin B6, riboflavin, selenium, copper, zinc, and pantothenic acid or B5. Slightly higher DV’s: Vitamin C, vitamin D, and calcium. These changes could have significant impact on health because of misstating the amount of needed nutrient.

The above is a brief summary from the article at Alliance for Natural Health. I highly recommend that you read the original article: FDA Needs a Lesson in Supplement Science  – Pandemic Survivor

Keep Them out of the Sun!

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Since this past fall, there has been an orchestrated campaign against the findings of health from vitamin D. The latest such attack has come from Dr. Mark Bolland, lead researcher in a recent finding. This in today’s Daily Mail: “He and his colleagues in the department of medicine at Auckland University, New Zealand, analysed the results of nearly 50 trials involving more than 200,000 people. They found that vitamin D supplements had little or no impact on the risk of heart disease, stroke, cancer or even bone fractures.”

From the same article, Professor Philippe Autier of France is even more blatant: “The vitamin D fad, he says, is just ‘a commercial promotion campaign’ in which sellers of supplements, UV lamps, fortified foods and blood tests are ‘taking advantage of disease-mongering around so-called vitamin D deficiency’”

Then there is this news release from Columbia University: “Study Finds No Evidence That Vitamin D Supplements Reduce Depression”

Given that they believe their own work, I think the solution is simple; keep them out of the sun for a year with no vitamin D supplements. If they survive this experience, then, we can see what type of diseases they have developed during this test. It all seems very reasonable to me. If they survive and develop no disease then we can say that they are correct. If they developed significant disease states, then this could be documented and their contribution to science and health would have been achieved.

We should also add the journalist to this cohort as well for just passing along information that is based on lack of logic and science. The number of people that have jumped on this band wagon should give us a very large cohort. I say lack of science because most of the studies reviewed are based on supplementation with very small amounts of vitamin D and second the studies are based on supplementation and not serum levels of vitamin D. Serum levels do not respond equally to supplementation or sunshine exposure.

Small amounts in supplementation in many studies are just ridiculous. Consider that we have long told the population of the world that all they needed was 400 IU of vitamin D daily. Studies have been based on this amount that is used to keep a ten pound (4.5kg) baby from getting rickets. So just how much vitamin D is this? 400 IU is equal to 0.01 milligrams or 10 micrograms. This is the amount that people with light skin color would make in about thirty seconds in the midday summer sun with sixty percent of their skin exposed. Okay, so let’s rewrite Dr. Bolland’s statement with this understanding: “They found that thirty seconds in the midday summer sun had little or no impact on the risk of heart disease, stroke, cancer or even bone fractures.” Hunh? I guess that I could have just figured that out without a study. What about thirty minutes in the midday summer sun Dr. Bolland? Isn’t that how we used to cure tuberculosis?

How easy it is to just jump on the ‘band wagon’ for a joy ride because everyone else says that it will be fun. Journalist, are you prepared to spend a year without sunshine to prove the scientist correct? I am glad I am not the person paying for these studies – wait, maybe I have through one of the divisions of Health and Human Services. Anyway, this type of logic almost killed me from severe sleep apnea to say nothing of three decades of pain. – “Disease mongering around vitamin D deficiency” – Pandemic Survivor

Wellness from the Sun has Changed Forever

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Henry Lahore of Vitamin D Wiki and with the help of others is putting out a video to help people understand how our relationship to the sun has changed over the last fifty years.  We have moved from outdoors to indoors.  Activities including work and play have all moved inside.  All of our energy for health which includes all the food that we eat comes from the sun.  Now, with sunscreens to shield us from the sun and sheltering inside, chronic diseases have increased significantly.

Highlights of the video include:

  • Diseases from low sun exposure
  • How food sources from decades ago were higher in vitamin D
  • How much vitamin D to take to get started
  • Blood test should be used to determine if your vitamin D level is high enough
  • The science behind the understanding of how vitamin D works for wellness
  • The video is to be made available so that it can easily be provided with voice over for eighty eight different languages
  • All of this in only five minutes in an easily understood format

One of the features of the video is a doctor that raised serum levels of vitamin D for his patients to 80 ng/ml.  This is well within the normal ranges of 30 to 100 ng/ml.  The patients in his clinic went from an average of four visits per year to one visit per year.  This statement should be significant in raising your awareness of the power of the sun and how it affects us and society as a whole.  I will let you know when this video becomes available. When it is available, please pass it along on face book, twitter, and any other public means that you have available. – Pandemic Survivor

Vitamin D3 Deficiency Causes Autism

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This is very exciting news!  Mechanisms have been discovered that shows how vitamin D deficiency causes Autism.  The authors’ state at the end of the abstract – Supplementation with vitamin D and tryptophan is a practical and affordable solution to help prevent autism and possibly ameliorate some symptoms of the disorder.

What happens next will be very interesting.  A government health department that was concerned for its citizenry would make a national response.  A special would be presented by the Surgeon General or/and the Secretary of Health and Human Services.  They would go on all the Sunday morning talk shows with this valuable information.  News organizations would pick this up to alert all expectant mothers of this new information.  Families that are now suffering the trauma of an Autistic child would have significant hope.  There would then be a follow up on Sixty Minutes.

Here is a digestible version of the news at Science Daily – Science Daily – Ames’ Study: Vitamin D causal link Autism

Yet, what we have are a few organizations striving to help people understand our connection to the sun and the value of vitamin D3.  Autism is just one of the many diseases that may be moderated by vitamin D3.  I am sure that the Vitamin D Council, Grass Roots Health, VitaminDWiki, and others will publicize this great information to the best of their ability.  But where is our government on this?  We will just have to wait and see. In the meantime, you are on your own in figuring out how to supplement.  All of the above mentioned organizations have information on how to do it. If you have an Autistic child, you may want to contact Dr. John Cannell, Vitamin D Council, on how to proceed with treatment.  Here is an interesting comment by one board certified pediatrician that wrote to him.  – Pandemic Survivor

Popeye Ashamed of his Government

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Popeye always saved Olive Oyl from the dastardly Bluto with the help of spinach.  It was thought at the time that the iron in spinach was the key to its ‘super properties’ and was promoted through the Popeye cartoons.  However, it is now known that the advantages of spinach are because of the large amounts of trimethylglycine and hydrofolate.  Both of these nutrients allows for the methylation cycle to occur for proper reading of your genetic map.

The FDA is now trying to keep the word folate, vitamin B9, off of labels for supplements.  Only folic acid, the synthetic form, is to be used.  This is an outrage on two fronts.  First, many people’s livers do not adequately process the synthetic form of folate, folic acid.  That is about thirty to forty percent of the population.  This increase of concentration of folic acid in the blood stream is thought to suppress the immune system and has caused an increase in lung, prostate, and colon cancer. Second, over sixty percent of the population has a mutation that reduces or prevents the enzyme, MTHFR, from being made.  This is the enzyme for completion of the conversion of hydrofolate into methyl folate.  Here is the complete story:  Alliance for Natural Health – ” Breaking News: FDA’s Sneak Attempt to Ban Another B Vitamin”

Poor Olive Oyl, what is she to do?  Will Popeye be strong enough to save her by supplementing with a man made molecule that was made in the laboratory in the 1940’s, folic acid?  Maybe a can of boiled spinach followed by a good punch in the eye of that dastardly FDA would do the trick.  Merck and FDA shaking hands to protect a market and create illness so that they can buy fast cars and appeal to Olive Oyl’s adventurous side is much worse than anything Bluto ever did.   “I’m through to the finish ‘cause I eats me spinach, I’m Popeye the sailor man.”  Ah, the days of super heroes when heroes were really super – Pandemic Survivor

Assault on the Nervous Systems by Anti-Cognitive Chemicals

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What do chloramines, fluoridation, lead corrosion, vitamin D deficiency, bromine, mineral sulfate removal, and iodine deficiency have in common?  They should all be classified as anti-cognitive biological chemical processes. We can be our own worst enemy.  We have been highly successful in our use of chemicals for technological advancement.  We try to protect ourselves from toxic substances and pathogens, while creating health problems through unintended consequences.  This has been the case for increases in Alzheimer’s, ADD, ADHD, Autism Spectrum Disorders, and other general cognitive impairment.  Halogen (iodine, bromine, fluorine, etc.) physiology along with mineral deficiencies needs to be significantly reviewed in the US and the use of halogens in our food supplies and water sources need to be adjusted accordingly.

Consider in the late 1990’s that the EPA decided it would be a really great thing to reduce the amount of chloromethane created from the chlorination of water.  They did this by forcing the use of ammonia added to water at the treatment plants creating chemicals in the water called chloramines.  Chloramines formed in water are so toxic that fish cannot live in it.  However, it is a longer lasting water disinfectant and it does not seem to generate as much chloromethane, a carcinogen.  However, the other toxic disinfectant byproducts (DBP’s) that are created and unregulated are of concern.  One of these may be halogen acetic acids.  HAA’s have a stated standard with standards for chloro-acetic acid and iodo-acetic acid, but no standard for fluoro-acetic acid.

Chloraminated water is much more corrosive, most likely from the created HAA’s.  This causes the leaching of lead from water pipes in supply and distribution systems (my city has thousands of miles of iron pipe held together at the joints with lead like must municipalities) and home potable water systems that are joined with solder lead joints.  There have been several studies showing an increase in lead content in water after the start of chloramination or the use of chloramines.

Fluoride has been shown to aid the build-up of the concentration of lead in the human body.  So by fluoridation of water to supposedly improve our dental health along with the use of chloramines, we have inadvertently created higher amounts of lead.  This is of major concern for the developing brains of our children and the aging brains of elderly.

The US is the only country in the world that allows the use of bromine in baking and in cloudy citrus drinks.  This iodine mimic causes significantly physiological malfunction in the thyroid as well as other functional biological iodine processes.  Consider that children have a ten to fifteen times higher uptake of iodine versus adults and consider the damage.  Bromine is not used in other countries because it is a carcinogen.

Add to this vitamin and mineral deficiency.  Vitamin D is responsible for mineral balance in the body, in particular the sodium-sulfate co-transporter.  Adequate sulfate is necessary for the formation of cerebroside sulfate that is necessary for proper neuron development.  Also consider that iodine deficiency is considered by the World Health Organization as the number one cause of mental illness in the world.  Sulfate also is the body’s best defense against toxins as it removes them through water soluble sulfate esters. Cities remove the sulfate minerals from the water because it is stinky and plugs the pipes.  Iodine, D3, and sulfate deficiencies combine as a disaster for mental function.

Take away iodine, vitamin D3, sulfate and add neuro-toxins and iodine mimics and you have the perfect conditions necessary for cognitive impairment.  Well the cause is idiopathic the experts claim.  Is Dr. M. Scott Peck accurate in his description of group evil through specialization?  One thing is certain, idiots and unintended consequences always seem to find each other.  In the case of water disinfection and vitamin and mineral deficiencies, you might say that this meeting of idiots and unintended consequences has created epicentric waves of causation for cognitive impairment.  For now, your cognizant commenter – Pandemic Survivor

Further Reading:

WHO on Nutrition for the CNS
Medscape Cognitive Deficits
“Limit Fluoride to Prevent Lead Poisoning” PRNews
Dr. Mercola on Chloramines
Wiki Autism Causes
VCE collection of Chloramine Science
Science Daily – Ames’ Study: Vitamin D causal link Autism

 

Deeper Sleep, Reduced Pain, Better Daytime Performance

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Sleep requirements, including quality, depth, and length of sleep are extremely important to health and a normal active day.  Stress is the major detractor of sleep in its many forms.  Whether it is stress from play, work, relationships, or physical pain, a downward spiral begins when stress is not relieved.  Of course the best mental stress reduction is to pray continuously or to meditate throughout the day for brief periods.  But what about the physical stress of pain?  Is there something simple that I can take that is safe that will allow me better sleep?  An absolute yes! GELATIN!

In the industrialized world, our diet has changed so that we are consuming primarily muscle meat protein.  It turns out that approximately fifty percent of the protein in the body is contained in collagen or in the cooked form, gelatin.  There has been such a push on reduced fat for heart health that many people confuse fat with gelatin.  They separate it from the cooked meat instead of making protein rich gravy as it was done fifty years ago on the typical American table.  It was always one of my favorite things as a child to feast on the rich gravies that my mother made.  It did not make any difference what type of meat we had.  There was always gravy. White flour gravy with chicken was just the right touch to savor with conversation after Sunday diner.  Dark brown gravy that accompanied the roast beef with the evening meal on a work night was fantastic.  After the meal, sleep came on with splendid ease.  Red eye gravy that we mixed with the grits for breakfast seemed to always make the day go much easier.

You have a cold that just want go away and your mother wraps you up in nice warm blankets and prepares a hot bowl of chicken soup.  Ah, how relaxing a mother’s love and chicken soup that seem to make the cold evaporate as vapors leaving with the morning sun.  What did that chicken soup have that was never associated with health benefits?  It was of course the chicken stock collected from cooking down remains of the last meal prepared with chicken.  The stock of course was collected from the pot that cooked down skin, bones, and chicken carcass. This stock was rich in peptides, amino acids, and proteins or from shorter to longer, the building blocks necessary for health.  And let’s not overlook the fats that are a part of the rich drippings that are necessary for the formation of hormones in the body as well as many other functions.

Let’s not forget the multiple arrays of gelatin deserts and punch mixes.  Fruit gelatin was a great desert that was not filled with added sugar or artificial sweeteners.  One of my favorites was cherry gelatin made with fresh ripe red cherries in early June.  Ah, the punches were just unbelievable for special occasions.  Ginger ale mixed in equal parts with pineapple juice with a pack of lime Jello added is just unbelievably good – mmmmmahhhh!  There is much sugar in this punch, but it was only served on special occasions.

It is bedtime and you have had a terrible day.  Go find that pack of gelatin without sugar added and wet the powder out in a small amount of cold water.  After the powder is wetted and dispersed, you can then further dissolved it in hot water with a sleepy time tea or other hot drink like warm milk.  Just plain gelatin does not have much taste.  I know one person that just mixes a whole packet of gelatin or about a tablespoon full with water.  She then slugs it down just before bed and claims an extremely restful evening and much clearer thinking the next day.  It seems the right amount of gelatin for relaxation is about one teaspoon for each fifty pounds of body weight.  In the morning, you can sprinkle gelatin on your oatmeal or put it in your favorite smoothy.

Let’s not forget the ladies in the farm neighborhood where I grew up that took gelatin to relieve joint pain.  Yep, that’s right, just plain old gelatin.  Their claims were that it would make their joint pain just disappear in a matter of hours after consuming gelatin.  But then again, they also ate lots of dark leafy greens that seemed to be the other part of this formula for joint relief.

So you don’t believe me and you want to mess up my pleasant memories of childhood with messy science that most likely has been manipulated for profit?  Then you are on your own, but if you have that bent, it is some extremely interesting reading.  See further reading below.  From your laid back and relaxed, healed from back pain, and sleep apnea with great enjoyment of life from appropriate micronutrients and the love of God and others; feel your stress dissolve and your pain fly away as you go to sleep little baby – Pandemic Survivor

Gelatin from Wikipedia
Gelatin, Stress, and Longevity – Ray Peat
GABA and Glycine
Vanilloid receptor-1 (TRPV-1)-dependant activation of inhibitory neurotransmission in spinal gelatinosa neurons of mice –
TRPV1; on the road to pain relief 
The effects of glycine on subjective daytime performance in partially sleep restricted volunteers 
TRPV1 from Wikipedia