Recently a clinical trial was started with 32 patients with many medical issues. P. R. Raghavan, Ph.D. has provided me with some of the initial results of the trail after thirty days. There are sixty markers for health being used in the study. The patients are being given 5 mg of per day of Metadichol (nano policosanol) and the markers being tested periodically.
The very interesting thing is that the vitamin D levels (25(OH)D) of the patients have improved by 38.2%. The baseline for the trial was an average of 12.75 ng/ml. After thirty days, the average of the group increased to 17.77 ng/ml. The following graph shows the results of 31 patients with one of the patients left out as there was no change in vitamin D. This gives the result of an increase for 31 patients at 39.4%. There was no supplementation of vitamin D or increased exposure to sunshine to account for this increase.
In Dr. Raghavan’s findings for Metadichol, he has shown through nuclear receptor studies that Metadichol can act as an agonist, antagonist, and as an inverse agonist for the vitamin D receptor. In conversations with Dr. Raghavan, he believes that Metadichol acts in place of vitamin D or as a helper to make the action of vitamin D more effective. He states that the vitamin D receptor is like the conductor of an orchestra to allow other nuclear receptors to properly react for health. I asked him how the nano policosanol knows how to control the receptors. He states that he believes it is through the communication of the genes in food with the human genome.
The details of the complexity of nano policosanol interaction with the human genome is yet to be completely determined. However, many thousands have taken Metadichol as a supplement in Asia for over a year with only positive results of health being reported. Policosanol is the waxy aliphatic alcohol that is found on the sun exposed portion of many plants. The Cubans have found in studies that policosanol is very effective in reducing total cholesterol and triglycerides and increasing HDL, the more desirable form of cholesterol for health. In addition, Dr. Raghavan has shown that Metadichol affects many of the markers for health which include blood sugar and insulin response. We will know more when the trial is completed. The Chinese have allowed the product to be marketed as boosting the immune system. It is particularly effective for wound healing and Dr. Raghavan also plans to show how Metadichol affects metabolic age.