Genetic Influence of Vitamin D

Vitamin D has been found to influence over 200 genes is a news article in  “Vitamin D status is potentially one of the most powerful selective pressures on the genome in relatively recent times,” says Professor George Ebers, Action Medical Research Professor of Clinical Neurology and one of the senior authors of the paper.”

We have discussed before the importance of vitamin D and its influence on genetics.  The findings in this study show that are 2776 binding sites for the vitamin D receptor along the genome.  This is a must read for those of you that like to assign the cause of disease to genetics.  This shows that even with a perfectly good gene map, if it is not being adequately activated by vitamin D, that many disease states can follow.

You may want to review a prior post on how vitamin D works with genetics.  D3 Epigenetic Master Switch.


2 thoughts on “Genetic Influence of Vitamin D

  1. Pingback: Vitamin D Testing – O Canada « Vitamin D Deficiency Survivor

  2. The active form of vitamin D is a steroid hormone. The power or strength of a steroid hormone can be measured by how many genes it can influence in a positive way, that is to say, to switch good genes on and bad genes off. There are 23,000 genes in the human genome, and Dr. Ebers’ research has found that over 10 percent are affected by 1,25(OH)2D. No other hormone affects such a large percentage of the human genome. Or to put it differently, no other substance known to man can make healthy changes to your genes as thoroughly as vitamin D.

    The impact of information is profound, game-changing, and life altering. If this were truly understood and embraced by mainstream medicine, and people everywhere were instructed by their doctors to optimize their vitamin D levels, the impact on public health would be enormous. One day vitamin D will take its place among the greatest scientific discoveries of all time

    Until then, those who optimize vitamin D will be seen as “early adopters” and they will blaze the trail for the rest of us. Eventually there will be enough so that the uppermost quartile in observational medical studies will have blood levels above 50 ng/mnL (or 125 nmol/L). The early adopters will have noticeably better health statistics and the stubborn side of the medical community will no longer be able to deny the obvious benefits.

    Mark, thank you for bringing this important information to the public eye. The pandemic is real, people are dropping dead by the millions, and they don’t realize why. I want to give all 6.5 billion inhabitants of earth this little bit of advice: Don’t die D-deficient. Can you please see to it they all get the message?

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